Glaucoma, "The silent thief of sight" is the 2nd leading cause of blindness globally. This chronic disease is profoundly prevalant across multiple continents, taking away millions of eyesights. Hong Kong, as a special administrative region of China, is located in the turmoil sea of Glaucoma, where POAG is popular in Asia.
Primary Open-Angle Glaucoma (POAG), our research topic, is the most common type of Glaucoma in the world. It is formed by the insufficient drainage of the aqueous humor, which increase the intraocular pressure (IOP) in our anterior chamber, and apply force to the surrounding tissues and cells of the eye. the increase of IOP then damages the Retinal Ganglion Cells (RGC), harming our vision.
The symptoms of Glaucoma is severe, suffering, and irreversible. The most widely-known symptom is the loss of vision, beginning from the peripheral areas. Other physical symptoms include acute eye pain, headaches, insomnia, etc. As a result, the symptoms not only cause extreme physical discomfort, but also heart-wrenching psychological effects to patients. Our team strives to devote to mitigating the problem.
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We are not alone in this iGEM journey. The development of this large-scale project involves various stakeholders in this society. Professors, patients, ophthalmologists, students, and more targeted groups, all provides us valuable insights on how to improve our projects in various aspects. We are deeply grateful for all your contributions and effort.
