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Education

Education

Our educational practice is a dynamic cycle that begins with listening and extends into a lasting legacy. Flowing like water, it nurtures the fertile ground of trust between science and society. Inspired by the spirit of "The ocean is vast because it admits all rivers," we begin at the headwaters of public concerns, channeling our efforts through thoughtfully designed responses to core issues, fostering an inclusive confluence that welcomes diverse participants, and ensuring that the outcomes of our work flow into a lasting river of knowledge for generations to come. This enduring cycle, from trust to legacy, embodies our commitment to building a responsible, vibrant, and inclusive future for synthetic biology.

Figure 1 Survey Promotion Poster

Figure 1. The Four-Stage Education Cycle

Building Trust: The Headwaters of Listening

Starting with Listening——A Public Perception Survey to Build the Foundation of Trust

Figure 1 Survey Promotion Poster

Figure 2. Survey Promotion Poster

Purpose: To map public awareness with precision, we launched this survey, aiming to use data to uncover genuine attitudes and knowledge gaps regarding synthetic biology and its applications in water treatment. The findings provide a reliable decision-making foundation for all follow-up activities, ensuring that trust is built upon sincere listening.

What We Did: The survey focused on whole-cell immobilization technology and collected 152 valid responses through structured questions. The data clearly revealed:

Figure 2 Results of the questionnaire survey

Figure 3. Results of the questionnaire survey

  • A significant 79.61% of the public expressed high or moderate concern about water pollution.
  • However, only 28.95% of respondents reported understanding the basic principles of synthetic biology, with over 70% being unfamiliar or entirely unaware of the field.
  • In terms of technological acceptance, over 76% of the public showed willingness to embrace the approach, yet their top concerns were potential ecological impact (86.84%) and reliability of biosafety mechanisms (78.95%).
  • Notably, after learning that engineered bacteria were equipped with a "safety switch," over 90% of respondents indicated increased acceptance of the technology.

Impact & Reflection

These key insights served as a "compass" guiding our subsequent initiatives:

  • Community and High School Activities: In response to the public's high concern yet low understanding, we engaged participants with explanatory demos and hands-on experiments like "Cleaning Dirty Water." Through themed pamphlets and exhibition content, we emphasized the safety mechanisms and practical efficacy of the technology.
  • University Competition: Participants were guided to align their projects with solving real environmental issues and to demonstrate the biosafety of their solutions during presentations, ensuring cutting-edge research resonates with public concerns.
  • Inclusive Education and Public Channels: The data reinforced the need for diversified science communication. By creating Braille stories and maintaining consistent content updates, we ensured that scientific knowledge reaches every member of the public, strengthening trust through inclusivity.

Responding to Needs: The Directed Flow

Community Event — A Fun Enlightenment of Synthetic Biology for Children

Figure 3 A group photo of the community event

Figure 4. A group photo of the community event

Purpose: Our preliminary surveys revealed public curiosity about the potential of synthetic biology, coupled with concerns about its safety. In direct response to these concerns, we designed this parent-child event. Starting from the headwaters of public interest, we aimed to translate complex scientific principles into reliable public knowledge, plant the seeds of scientific exploration in children's minds, and create an inclusive space for families to engage in scientific practice together.

Figure 4-1 Community event poster
Figure 4-2 Community event poster

Figure 5. Community event posters

What We Did: Guided by the principle of "learning through play," we meticulously planned a science workshop that integrated storytelling, theoretical explanation, and hands-on practice.

Scientific Storytelling: We instantly captured the children's interest by framing the activity around the mission of "Saving the Dirty Water." A brief introduction to synthetic biology and the iGEM project connected the scientific background of TasAnchor to the practical problem of water pollution, making advanced science relatable.

Figure 5 The host is explaining iGEM

Figure 6. The host is explaining iGEM

Exploratory Hands-On Practice: During the hands-on session, families collaborated to build simple water filters from everyday materials like plastic bottles, activated carbon, sand, and gravel. We guided them through a standard design and further encouraged the children to become "young engineers," modifying the filter structure (e.g., adding more activated carbon layers or changing the material order) to explore more efficient purification solutions. This process transformed the abstract concept of "filtration" into a tangible, personal experience.

Figure 6-1 The children excitedly built simple sewage purifiers
Figure 6-2 The children excitedly built simple sewage purifiers
Figure 6-3 The children excitedly built simple sewage purifiers
Figure 6-4 The children excitedly built simple sewage purifiers

Figure 7. The children excitedly built simple sewage purifiers

Impact & Reflection:

Building Trust & Igniting Interest: The children's surprise and sense of accomplishment upon seeing the clean water they had filtered was the most direct validation of science's appeal. At the end of the event, many children not only took their homemade filters home but also requested extra materials to continue experimenting independently. This proves the activity successfully "filtered" environmental awareness and scientific curiosity into their hearts.

The Value of Inclusive Engagement: Serving as an inclusive confluence, the event enabled not only children to learn but also parents to participate and witness, effectively strengthening parent-child bonds and allowing scientific knowledge to ripple more broadly through the community via family units.

Our Legacy & Growth: The success of this event is not merely an endpoint, but a powerful testament to the vitality of the "Science-Play-Harvest" educational model we have built with the community. We were delighted to see the seeds of science sown last year beginning to sprout — several familiar young faces, returning participants, joined us again with greater interest and deeper understanding. Their return, driven by trust and enjoyment, is the most vivid affirmation of our educational model's effectiveness.

Figure 7-1 The special filters created by children
Figure 7-2 The special filters created by children
Figure 7-3 The special filters created by children

Figure 8. The "special" filters created by children

High School Science Festival——Building a Bridge between Science and Youth

Figure 8 Set up a stall at Sichuan Chengdu Shude High School

Figure 9. Set up a stall at Sichuan Chengdu Shude High School

Purpose: This event, held at the Shude High School Science Festival under the theme "Strengthening the Nation through Technology · The Future is Ours," aimed to introduce high school students to synthetic biology and foster their scientific interest. Through face-to-face interactions on campus, we sought to break down disciplinary barriers and present synthetic biology in a vivid and accessible way outside the lab. Using our SCU-China 2024 project, Versatobacco, as a case study, we helped students understand the engineering mindset and the Design-Build-Test-Learn (DBTL) cycle in synthetic biology, demonstrating its potential to solve real-world problems, ignite passion for research, and plant seeds for future talent.

What We Did: The activity took the form of an innovation exhibition booth, creating a science communication platform that integrated knowledge dissemination, hands-on experience, and creative expression.

Building a Knowledge Framework: We designed and printed illustrated brochures that systematically introduced the basics, applications of synthetic biology, the iGEM competition, and the achievements of SCU-China's past projects, providing students with a structured knowledge base.

Figure 9-1 Community event poster
Figure 9-2 Community event poster

Figure 10. Detailed content of the brochure

In-Depth Case Study Explanation: Using the Versatobacco project as a core example, our team members explained how synthetic biology can be used to engineer tobacco plants for diversified functions, allowing students to intuitively appreciate the appeal of bioengineering.

Creative Hands-On Practice: We innovatively introduced a heat shrink plastic sheet art activity. Guided by our members, students drew scientific elements like the iGEM logo and DNA double helix to create unique keychains, transforming abstract knowledge into tangible creative artifacts.

Figure 10 The students draw heat shrink sheet pendants

Figure 11. The students draw heat shrink sheet pendants

Impact & Reflection:

Stimulating Deep Critical Thinking: The students showed strong interest and curiosity. They not only listened attentively but also proactively asked deep questions about gene editing, biosafety, and the ethics of synthetic biology, demonstrating excellent scientific thinking.

Merging Creativity and Practice: The shrink film activity greatly stimulated students' creativity. By combining scientific elements with art, they deepened their understanding of the symbolic language of synthetic biology through hands-on practice.

High Praise and Lasting Impact: Teachers from Shude High School highly praised this interactive model as a valuable supplement to classroom teaching. Follow-up feedback revealed that the activity sparked a strong interest in biological sciences among some students, with some even expressing a desire to participate in iGEM in the future. This experience has provided us with invaluable insights for tailoring science communication to different age groups.

Sichuan University Applied Cellular and Molecular Activities Competition (ACMA)——An academic competition that broadens diverse horizons

Figure 11 The host introduced the rules of the competition

Figure 12. The host introduced the rules of the competition

Purpose: To deepen the educational cycle "from trust to legacy," we continued and enhanced the Sichuan University ACMA competition. We aimed to create an inclusive, interdisciplinary academic platform that inspires students to proactively explore the frontiers of synthetic biology, translate classroom knowledge into innovative solutions for global challenges, and in doing so, cultivate the next generation of capable and responsible scientific talent.

What We Did: This year's ACMA competition featured challenging tracks including "Natural Product Synthesis," "Environment," and "Therapeutics," attracting teams from diverse disciplinary backgrounds.

Exploration of Cutting-Edge Topics: Participants were required to independently complete the entire process from literature review and project design to final presentation and defense. This year's award-winning projects were highly pioneering and relevant, tackling issues such as PET microplastic pollution through a collaborative bacterial system, precision immunotherapy for advanced liver cancer using a novel viral agent, and high-efficiency photo-biological hydrogen production from cyanobacteria via a dynamically regulated circuit.

Figure 7-1 The special filters created by children
Figure 7-2 The special filters created by children
Figure 7-3 The special filters created by children

Figure 13. The tense and exciting defense process of the contestants

Impact & Reflection:

Igniting Interdisciplinary Innovation: One non-biology major participant noted, "I knew nothing about ACMA at first. An upperclassman recommended it, so I thought I'd give it a shot. To my surprise, the competition turned out to be way more professional than I expected, and I realized synthetic biology actually has huge potential in my own field too." This confirms that our platform effectively stimulates deep academic critical thinking and strengthens the bond of trust between science and society.

Achieving Continuous Knowledge Legacy: The ACMA competition has become a cornerstone of the synthetic biology education ecosystem at our university. We are delighted to see that outstanding ideas born in the competition are serving as prototypes for advanced research projects like iGEM. This ensures a continuous flow of innovation, ultimately feeding into the lasting river of knowledge for future generations.

Figure 4-1 Community event poster
Figure 4-2 Community event poster

Figure 14. Teachers and award-winning seniors offered guidance to younger students

Inclusive Participation: The All-Embracing Watershed

Educational initiatives for the visually impaired------Creating Barrier-Free Science Education for the Visually Impaired

Purpose: Education strives to ensure that the fertile soil of science nourishes everyone. We recognize that the visually impaired community often encounters barriers in accessing cutting-edge scientific information. This project was born from the need to break down these information barriers, creating a truly accessible and engaging world of synthetic biology for children with sight loss. Our goal is to allow the waters of knowledge to flow freely and equitably to every eager mind.

What We Did: We moved beyond a single medium to create a multi-dimensional science experience that integrated touch, sound, and storytelling.

Original Bilingual Science Story: We have created a tale about synthetic biology, framed within the beloved rivalry of " Pleasant Goat and Big Big Wolf". Through the playful conflict between the characters, we naturally introduce core concepts like "Synthetic Biology" and "Genetic Modification," transforming complex science into an easy-to-understand narrative.

Fully Accessible Formats: To ensure knowledge knows no bounds, we produced four versions: Chinese Braille, English Braille, Chinese audio drama, and English audio drama. The audio dramas were not mere readings; we used open-source AI models to clone character voices and performed professional editing, resulting in a vibrant production of broadcast quality.

English Audio
Chinese Audio

Impact & Reflection:

Building Trust Beyond Barriers: Through tactile (Braille) and auditory (audio drama) channels, we strive to open a new window to synthetic biology for visually impaired children. This program represents a key step in our effort to build inclusive science practices. Its multi-sensory and engaging design is specifically intended to transform seemingly distant synthetic biology concepts into experiences that are perceivable and understandable.

Creating a Replicable Legacy of Inclusion: The complete suite of resources we have developed---including the bilingual story script, bilingual braille documents, and the bilingual radio drama---has been compiled into a freely accessible resource kit. This ensures our project can flow like water, continuously reaching and nurturing more communities.

Sustaining Legacy: The Perpetual Return

Official Accounts——Building a Platform for Ongoing Practice and Knowledge

Purpose: The highest value of education lies in its continuity. To transcend temporal and spatial limits and transform the sparks of interest ignited by our offline activities into a self-sustaining flame, we have built and actively maintain the SCU-China WeChat Public Account. More than a mere chronicle of events, it serves as the digital hub for our spirit of "inclusive excellence," aiming to build an open-access knowledge repository for a broader audience that continuously accumulates and evolves, ensuring the insights from every initiative flow into the enduring river of knowledge.

What We Did: Serving as the online cornerstone for all our endeavors, the public account systematically hosts two core types of content:

  • Documenting & Reflecting on Practices: It promptly publishes detailed reports with visuals from all our events. These posts go beyond showcasing outcomes to include deep analysis of our activity design, public feedback, and project impact, turning practical experience into structured knowledge for others.
  • Exploring & Interpreting Scientific Depth: Dedicated columns provide accessible explanations of key scientific literature and technological breakthroughs in synthetic biology. We also continuously track and analyze innovative projects from iGEM teams worldwide, distilling their design concepts and engineering logic to offer our followers a continuously updated window into academic frontiers.
Figure 14-1 The official account of igem Student Club
Figure 14-2 Published articles of igem Student Club
Figure 14-3 Published articles of igem Student Club
Figure 14-4 Published articles of igem Student Club

Figure 15. The official account of igem Student Club and some articles it has published (welcome everyone to follow!)

Impact & Reflection:

A Trust Bridge Connecting Online and Offline: The account allows the impact of each offline event to be documented and amplified. Participants can revisit activity content, while those unable to attend can access knowledge regardless of location. This establishes a stable information channel that continuously strengthens the bond of trust between the public and science.

Building a Sustainable Cycle of Legacy and Impact: The teaching materials, activity templates, and literature analyses archived on the platform have become vital tools for internal knowledge transfer within our team and the best guide for new members. Furthermore, these high-quality open resources are being referenced and used by a growing number of groups both on and off campus.

Conclusion

With a series of thoughtfully designed initiatives—from interactive science workshops to academic competitions, from campus tech festivals to barrier-free education—we have witnessed how the educational cycle of "Listening-Responding-Including-Inheriting" flows like a continuous stream, effectively nurturing understanding and passion for synthetic biology across ages and backgrounds. This cycle, beginning with trust and expanding through inclusion, has now matured into a self-sustaining force of inspiration and inheritance. We look forward to its ongoing ripple, inviting more future minds to explore, engage, and excel in this vibrant field.