And We Are Here to Checkmate Cancer.
Cancer is one of the leading causes of death worldwide, with lung cancer being the most common cancer type.
Cancer demands more than a single move – it requires a master's strategy. Like chess, defeating cancer takes precision and the coordinated power of multiple pieces working in perfect harmony.
With innovative concepts and predictive tools, our solution is designed to effectively target cancer cells while minimizing the effect on healthy cells.
Meet our solution to lung cancer!
Our platform uses a synthetic, chemically modified DNA strand called an Antisense Oligonucleotide (ASO), which is conjugated to an antibody.
Vascular Delivery
After entering the body, the platform circulates through the bloodstream.
Reaching the lungs
From the bloodstream, it is delivered directly to lung tissue.
Targeting cancer cells
The antibody binds specifically to receptors that are overexpressed on lung cancer cells, enabling the platform to enter the cancer cell.
Silencing a vital gene
Inside the cell, the ASO binds to a messenger RNA (mRNA) transcript of a gene essential for cancer cell survival.
RNA Knock-down
The ASO–mRNA complex is recognized by cellular enzymes, which degrade the mRNA and reduce the gene’s expression.
Antibody processing
The antibody used for delivery is broken down into short peptides, one of which is a neoepitope specific only to the lung cancer cells.
Immune system activation
This neoepitope is displayed on the cell surface by MHC molecules, where it is recognized by immune cells.
Cancer cell destruction
Recognition of the neoepitope activates an immune response that flags the cancer cell as a threat - leading to its elimination.
Our computational approach leverages a comprehensive feature set that balances on-target therapeutic activity with off-target safety considerations, enabling our proprietary software platform to generate optimally effective and efficient ASO sequences.
The fight against cancer isn't won with single moves - it's won with sophisticated strategies that adapt, evolve, and never give up. Join us in checkmating cancer.
