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Overview

This year, our education initiative set out with one main goal: to reach more than 15,000 people with our educational program . At the end, we had carried out +30 visits, which had a direct reach of almost 19,756 people.

Figure: Pulsatile vs. continuous release
Figure: Pulsatile vs. continuous release

We began with a survey that showed clear gaps in public awareness of asthma and synthetic biology. It also highlighted vulnerable groups, such as workers in certain jobs and hospital patients, so we focused on them. The team reached more than 10 high-risk occupations and several health institutions, including hospitals and pharmacies. Since children are among the most affected by asthma, we prepared family-focused resources: a guidebook for parents, a storybook for kids, and posters with tips on handling triggers like pets at home.Additionally, we made sure that all our content would be easily accessible & downloadable on every social media platform to obtain sustainability for PRESS. All patients' images & personal data has been shown on this page after taking detailed consent & permission from the patients themselves. We ensure their privacy is respected according to ethics guidelines.

Survey
Figure: Pulsatile vs. continuous release

We based our plan on 3 important pillars: synthetic biology, soft skills, and awareness of asthma. All our activities were also tailored to the age group we were dealing with, ranging from young children in kindergartens to the geriatrics and public.

We ran 2 parallel sessions: one on asthma prevention and management, and another on synthetic biology basics and soft skills. We also spoke with policymakers to show how this field can lead to practical healthcare solutions.

To make learning engaging, we went beyond lectures. We used songs, games, graphic stories, posters, workshops, and interactive activities. Online, our reach expanded through videos and a podcast in five languages:English, French, German, Spanish, and Chinese. In addition, we translated our asthma guidebook, synthetic biology guidebook, and children's story into Arabic, English, Chinese, and Greek through a collaboration with the IGEM Ionana team, for wider impact. To enhance accessibility, we translated our asthma and synthetic biology guidebooks into Braille and made them available at main public libraries for the visually impaired community.

Asthma guidebook

Asthma guidebook EN

Asthma guidebook Greek

Synthetic biology guidebook

Synthetic biology guidebook EN

Synthetic biology guidebook Greek

Synthetic biology guidebook Chinese

Synthetic biology guidebook Arabic

References

  • Garner K. L. (2021). Principles of synthetic biology. Essays in biochemistry, 65(5), 791–811. https://doi.org/10.1042/EBC20200059

  • Wang, Y. H., Wei, K. Y., & Smolke, C. D. (2013). Synthetic biology: advancing the design of diverse genetic systems. Annual review of chemical and biomolecular engineering, 4, 69–102. https://doi.org/10.1146/annurev-chembioeng-061312-103351

  • Yang, L., & Lu, Q. (2025). Beyond Cutting: CRISPR-Driven Synthetic Biology Toolkit for Next-Generation Microalgal Metabolic Engineering. International journal of molecular sciences, 26(15), 7470. https://doi.org/10.3390/ijms26157470

  • Kumaran, A., Jude Serpes, N., Gupta, T., James, A., Sharma, A., Kumar, D., Nagraik, R., Kumar, V., & Pandey, S. (2023). Advancements in CRISPR-Based Biosensing for Next-Gen Point of Care Diagnostic Application. Biosensors, 13(2), 202. https://doi.org/10.3390/bios13020202

  • Zhao, M., Tanourlouee, S. B., McCracken, S., & Williams, P. R. (2025). Genetically encoded biosensors of metabolic function for the study of neurodegeneration, a review and perspective. Neurophotonics, 12(Suppl 2), S22805. https://doi.org/10.1117/1.NPh.12.S2.S22805

  • Burgos-Morales, O., Gueye, M., Lacombe, L., Nowak, C., Schmachtenberg, R., Hörner, M., Jerez-Longres, C., Mohsenin, H., Wagner, H. J., & Weber, W. (2021). Synthetic biology as driver for the biologization of materials sciences. Materials today. Bio, 11, 100115. https://doi.org/10.1016/j.mtbio.2021.100115

  • Banner, A., Toogood, H. S., & Scrutton, N. S. (2021). Consolidated Bioprocessing: Synthetic Biology Routes to Fuels and Fine Chemicals. Microorganisms, 9(5), 1079. https://doi.org/10.3390/microorganisms9051079

  • Moore, J. C., Ramos, I., & Van Dien, S. (2022). Practical genetic control strategies for industrial bioprocesses. Journal of industrial microbiology & biotechnology, 49(2), kuab088. https://doi.org/10.1093/jimb/kuab088

  • Jefferson, C., Lentzos, F., & Marris, C. (2014). Synthetic biology and biosecurity: challenging the "myths". Frontiers in public health, 2, 115. https://doi.org/10.3389/fpubh.2014.00115

Story

Story EN

Story Greek

Story Chinese

Story Arabic

While doing this, we connected our work to the UN Sustainable Development Goals(SDGs),namely SDG 4 (Quality Education) and SDG 15 (Life on Land), emphasizing the broader extent of our work.

The team showed how the educational program directly contributed to shaping PRESS as a product, and ended by sharing feedback and quotes from participants that encouraged them to keep moving forward with passion.

Tutorial

    When documenting education, we realized that impact shows best when there is both a bigger picture structure and a detailed event record. That is why we suggest two tools for future iGEM teams:

  • A page style tool, which organizes the whole Education page into clear sections and a timeline that connects every stage.
  • Page Style Tool

    1. Journey Timeline

    Build a timeline of your education activities.

    Figure: Pulsatile vs. continuous release

    Divide it into two parallel tracks:

    Track A: Project-related science topics (e.g., synthetic biology, genetics, disease mechanisms).

    Track B: Soft Skills and awareness (e.g., communication, health literacy, sustainability).

    For each age group, include 3 interactive entries:

    Science/ Soft Skills Event.

    Project/Health Event.

    End with policymakers/experts: share your science, and record the guidelines or advice you receive back.

    2. How Education Shaped the Project

    Create a short timeline showing how each education stage influenced your:

    Idea or design decisions.

    Communication strategies.

    Human Practices approach.

    Keep it brief: 1–2 sentences per stage.

    3. Focused Outreach

    Dedicate activities to groups most affected by your problem (e.g., high-risk patients, key users, or vulnerable communities).

    4. Feedback

    Collect direct quotes, questions, or reflections from participants.

    Present them as a "mirror" of your journey, showing real impact and community voice.

    Why This Tool Works

    Inquiry-Based Learning: every activity links to a clear outcome.

    Kolb's Learning Cycle: move from experience → reflection → application.

    Community-Based Research: value feedback as much as teaching.

    By following this tool, any iGEM team can turn education into more than reporting. It becomes a living framework to track progress, reflect on impact, and design human-centered solutions.

    An Application for the tool:

    1. Our Journey

    A timeline divided into two parallel pathways: synthetic biology & soft skills on one side and asthma awareness on the other. For each age group, we provide three interactive buttons:

    • Age: materials and activities for that stage

    • Synbio & Soft Skills Event

    • Asthma Events

    • The journey concludes with our discussion with policymakers, where we shared new synthetic biology principles and, in return, learned about regulations and manufacturing guidelines. Each event is labeled with its key theme, reflecting the diversity of topics and our effort to tailor them to the right audience.

    2. How Education Shaped PRESS

    A concise timeline showing how every stage of our outreach influenced the design of PRESS. This reflects our commitment to building a human-centered product that responds to real community needs.

    3. Focused Outreach

      Special sessions designed for high-risk asthma groups, ensuring that our educational materials reached those who need them most.

      4. Feedback

      Quotes and reflections collected along the way. It was a mirror of our impact and a source of motivation that guided our entire journey.

  • An event tool, which provides a consistent way to document each single activity, from overview to impact.
Event Documentation Tool

For every event, document it using five core elements:

Overview

Figure: Pulsatile vs. continuous release

Short summary of the event.

Include who the audience was, what the main topic was, and the format of the session.

Why It Matters

Explain the purpose of this event.

Link it to your project, community need, or global challenges (e.g., SDGs, public health).

Activities

Describe what actually happened during the visit/session.

Mention tools used (posters, role-play, songs, workshops, demos, etc.).

Keep it factual and concise.

Impact on Us (the team)

What you learned from the event.

How it changed your approach, communication style, or shaped your project design.

Skills gained (e.g., public speaking, adapting science to audience level).

Impact on Them (the audience)

What participants gained in knowledge, skills, or awareness.

Include quotes, feedback, or reflections if possible.

Add a pre/post graph to visualize the effect of the event on their knowledge.

Why This Tool Works

Makes every event structured and comparable across the project.

Forces teams to reflect on both sides: what we gave and what we got back.

Captures both quantitative (graphs, scores) and qualitative (stories, quotes) impact.

Grounded in trusted frameworks:

Kolb's Experiential Learning Cycle → experience → reflection → application.

Inquiry-Based Learning → questions and curiosity drive deeper understanding.

Community-Based Participatory Research (CBPR)

Education Evaluation Models (input–process–outcome–impact) → make results measurable and clear.

This approach turned our education page into more than a record. It became a way to show impact, share lessons, and build trust — a method any future iGEM team can rely on.

An Application for the tool

For every event, we captured the following elements:

  • Overview – a summary of the event and its activities.

  • Why it matters- the importance of introducing this event.

  • Activities – what actually happened during the visit.

  • Impact on us – the lessons we shared, what we learned in return, and how the experience helped shape the direction of our project.

  • Impact on them - what is gained by the targeted audience through all the activities we conducted, with a graph representing pre and post effect on their knowledge.

This approach turned our education page into more than a record. It became a way to show impact, share lessons, and build trust — a method any future iGEM team can rely on.

Our journey

Focused Outreach

High risk occupations

Overview

Through our survey, we found that some occupations carry a much higher risk of asthma than others. This motivated us to conduct an educational program toward these workers. Using both our survey results and official data from the Central Agency for Public Mobilization and Statistics, we ranked the occupations most affected, as shown in the graph below:

Figure: Pulsatile vs. continuous release
Figure: Pulsatile vs. continuous release

During these visits, we started by introducing asthma and how it develops. We explained in clear terms how both genetics and environmental exposures play a role. We highlighted the main warning signs that should push someone to see a doctor. We also gave hands-on training on proper inhaler technique. Each participant practiced until they felt confident, while we showed visuals of the side effects caused by incorrect techniques to stress why proper use matters. In order to make sure the message reached beyond the workplace, we handed out our guidebook so they could share the information with their families.

For every occupation, we outlined their respective risk factors and common triggers to which they are exposed, along with feasible measures for evading them. We also provided personal protective equipment (PPE) suitable for every type of work. Additionally, we provided simple lifestyle behaviours that reduce their likelihood of exposure and protect their health in the long run. Finally, we conducted follow-up visits to these occupations to ensure their commitment to what we demonstrated like wearing their PPEs and following occupational lifestyle behaviors. Nearly 91% of the workers were committed.

Why it matters
  • We focused on workers in high-risk jobs, ensuring that support reached those who needed it most.

  • Demonstrating ways for prevention helps cut down asthma attacks and reduce the need for hospital visits.

  • Encouraged simple lifestyle and workplace changes that built lasting habits, linking health education with SDGs.

Impact on Them
  • Workers became aware of how their daily activities expose them to asthma triggers.

  • They learned hands-on strategies like mask use, ventilation, wet sweeping, and safe handling of chemicals or animal waste.

  • They learned to spot warning signs early and practiced the correct way to use an inhaler.

  • Many realized prevention is better than treatment, such as choosing low-VOC paints or using filters.

  • Some became advocates: farmers promoted tree planting, and pet shop owners displayed posters for customers.

  • The visits helped reduce stigma around asthma, showing it’s a real but manageable condition.

  • Handing out guidebooks ,alongside our advice, made workers and families more confident in spotting and managing symptoms early.

Impact on Us
  • We built empathy by hearing workers’ stories on poor safety, their children’s struggles, and medication side effects.

  • The team learned awareness programs must be simple and affordable, like cloth masks, composting, or safer work practices.

  • We realized that workplaces, not just schools and hospitals, are crucial spaces for health education.

  • A key gain was cultural exchange, as farmers taught us tree planting as part of sustainable practices.

  • Our team improved its teaching by using posters, flashcards, and visuals instead of long lectures.

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Bakeries

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Painters

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Vet Master Clinic

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Cleaners

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Wood factory

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Pet shops

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Spinning & Weaving factory

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Agriculture

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Animal waste managment workers

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Sand quarries

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Brick factory

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Bakeries

7th of June 2025

We visited 5 local bakeries and spoke with the workers. We explained the risk of the massive amounts of flour and yeast dust they are exposed to on a daily basis. We introduced "baker's asthma", a disease that results from such exposures, and stressed that prevention starts at the source. We suggested they pour flour slowly, operate mixers with low speed until ingredients are fully mixed, wear masks and improve ventilation with filters or windows.
We also stressed the importance of reporting early symptoms instead of suppressing them. Lastly, we handed out our guidebook in an attempt to inform individuals about asthma and its indicators. This visit proved how work settings as bakeries can trigger or worsen asthma and how simple it is to maintain workers' health.
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Painters

17th of June 2025

During our awareness program, we visited painters as they get exposed to paint vapors that severly damage their lungs. We met with Mr.Ahmed who started painting at the age of 18; he rarely used PPE in his early years of working. During his following years, he started experiencing shortness of breath, coughing, dizziness, and having the occasional headache which he had been ascribed solely to working continuously.
In our conversation, we stressed that using proper PPE can protect his lungs and prevent asthma exacerbation. We clarified that using water-based paints has less harm on lungs than oil-based ones due to volatile oil components (VOCs). We recommended working in well-ventilated areas rather than closed ones.
At the end of our session, Mr. Ahmed mentioned that he had previously attempted to learn about asthma online but he got lost by medical terms' complexity. This pointed out the importance of providing simple and accessible health education online. In an effort to make our asthma handbook easily accessible, we uploaded it online; we also handed Mr. Ahmed a hard copy.
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Healthy Pets, Healthy Lungs: Our Asthma Awareness Visit to Vet Master Clinic

22nd of June 2025

We went to a small vet clinic to talk with both the doctors and pet owners about asthma. We started with explaining how pets can induce asthmatic triggers. Things like dander, fur, or even saliva can make asthma worse.
Following that, we shared some easy tips. For example, don’t let pets sleep in the bedroom, brush them outside, keep the house clean with simple sprays, and use filters if possible. We also reminded them to wash their hands often and to check their pets regularly. As for the owners, we showed the right way to use inhalers and asked them to pass this knowledge on to family or friends.
We learned how the vets keep their place safe: open windows for fresh air, always wear gloves & masks, and clean carefully.
Before leaving, we provided posters and simple guidebooks. The clinic staff stated that the materials would help, and they planned to share them with other pet owners.
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Cleaners

10th of June 2025

We began by discussing the irritants cleaners face at work and correcting some common misconceptions. Many of them believed their cough or breathing problems were just infections, without realizing that cleaning products and dust were often the real triggers. We showed them examples such as bleach, fumes, dust, and even pet dander.
We then gave them practical advice on how to reduce exposure. For instance, we advised them why sweeping in areas with poor ventilation would only aggravate things and instructed them to leave the windows or doors open while sweeping. We also instructed them to wear masks to reduce inhalation of fine particles.
We offered some further guidance prior to leaving, including choosing cleaning products with lower volatile organic compounds. They would be significantly less irritating for asthma patients. During the discussion, Mr. Shady, a patient, mentioned that it was increasingly challenging to manage his diabetes since starting asthma therapy. This was a reminder of the importance of considering xside effects and individualized management. Lastly, we gave them our poster that demonstrates common cleaning triggers and how to stay safe.
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Wood factory

3rd of July 2025

We went to a wood factory and saw how much dust fills the air when workers cut, saw, or sand the wood. Some of them already had coughing and allergies from this daily exposure.
We talked about simple protection. A mask & a pair of goggles can go a long way. We also stated that vacuum machines are safer than using air pressure, which only spreads the dust around. Another mistake we noticed was that many workers only worry when they smell something strong. The team mentioned how chemicals like VOCs or formaldehyde in pressed wood may be odorless, but they are still dangerous if breathed in for years.
At the end, we told them that protecting yourself is not only about health, but it also means fewer sick days and better work performance.
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Pet shops

12th of June 2025

We learned from the Asthma and Allergy Foundation of America (AAFA)that pet dander can make asthma worse for most patients. For that reason specifically, we decided to include pet waste management in our awareness work this year.
Our team visited several pet shops and talked with workers about how to control dander, mold, and waste. We explained how these can affect the breathing of people with asthma and why proper cleaning is important.
In order too make it simple, we designed a clear poster. The first part shows how animal waste can harm people with asthma. The second part explains what to do: wear a mask & gloves, scoop & bag the waste, wash the area with soap & water, and finish with proper hand washing.
We also advised shop owners to clean regularly, keep the place tidy, and use protection when handling pets. Many liked the poster idea and asked for extra copies to share with their customers. By the end of our visit, it was clear that simple visuals helped get the message across in an easy way.
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Spinning & Weaving factory

1st of July 2025

We visited the spinning and weaving factory, where the air was filled with flying cotton fibers and fine dust. The smell of chemical dyes was also strong and irritating as we moved between sections.
After the tour, we sat with the manager, to talk about the workers’ health and the importance of regular check-ups. When we asked the employees during interviews how it is to work alongside dust and fibers all year round, they explained how challenging it was. Several tried to cover their faces with rags or used shifts in rotation in attempt to cope. We explained that these steps are not nearly enough to protect their lungs and revealed much safer options, including wearing the right N95 masks, keeping the work area well ventilated,and using safer dyes.
In the course of our discussion, some workers inquired what would happen if they continued to breathe in fine particles for decades. We explained that long exposure can cause asthma or even a disease called byssinosis, more commonly known as brown lung. Many were astonished, confirming the importance of awareness visits in such jobs. We reiterated that regular doctor visits and wearing protective equipment at all times can mean a great deal.
One of the workers ,who suffered from asthma for a long time, shared with us that he often missed taking his medicine on time because the treatment was complicated and confusing. This made us realize another challenge: even when patients know what they need, complicated routines can stand in their way.
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Clean Farms, Clear Lungs

16th of June 2025

As part of our educational program and aligning with SDG 15 (life on land), we visited Mr. Saber's farm and talked to him and the other farmers about the contribution of agriculture towards health and the environment. We explained how dust and pollen are aggravating factors in asthma, while trees are a natural air filter. As part of our plantation drives.We also uncovered that we have been a part of the ongoing 100 Million Trees project;they were very receptive to such idea.
We also discussed other harmful practices like stubble burning and spraying pesticides without protection. Burning of crop waste creates dense smoke that pollutes the environment and triggers asthma;therefore, we suggested we use it as livestock feed. Farmers showed us simple procedures in planting a tree: choose a sunny spot, plant it, and give it water.
Additionally, we visited flower shops to raise awareness about ashtma. We told staff that pollen and perfumes from flowers can trigger asthma attacks. We recommended practical solutions: use proper ventilation, avoid strong-scented sprays, and keeping highly allergenic flowers separate.
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Tackling Asthma through Animal Waste Management

27th of June 2025

We visited the village and saw animal shelters where animal waste was thrown into the corners. We educated the farmers about how it affects air quality and worsens asthma among residents nearby.
We did this collectively, proceeding through simple steps to manage waste: collecting it every day, turning it into compost, and subsequently using it as manure in the soil. Seeing how it could improve their land and make the world cleaner, the farmers experimented with waste management with us along their side step by step.
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Sand quarries

4th of July 2025

Our team organized an awareness tour to a neighborhood sand quarry where many workers suffer from respiratory complications caused by inhaling heavy dust on a daily basis. We demonstrated how airborne fine particles can cause irritation in the airways, worsen asthma, and in the long term lead to silicosis.
During the session, we focused on hands-on practices to limit exposure. We stressed the need for respiratory protection—even a simple cloth mask is better than nothing, though proper masks are best. We also advised on reducing dust from the source by wetting sand piles before handling them and avoiding dropping sand from high places.
Another important point we raised was working upwind whenever possible, rotating shifts to reduce exposure, and replacing dry sweeping with wet methods. The workers were present and also gave us their feedback. One guy told us that since he started taking asthma medication, he gained a lot of weight and could no longer fit into his clothes. His doctor told him that this was a side effect of the medication.
Through this visit, we concluded that most of the workers did not know about the long-term risks. Therefore it was important to keep such awareness programs ongoing.
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Brick factory

21st of June 2025

The day we visited a brick factory, we discussed the health hazards that arise when fine dust is emitted. This happens all the way through the manufacturing process with workers inhaling it on a daily basis. We met one of the workers, Mr. Said. He began working there at the age of 22 without proper safety precautions.By the time he was 35, he had contracted asthma following years of exposure. He also experienced increased infections after taking the asthma treatment, which made him even more anxious.
We educated the workers that simple steps—like wearing high-efficiency masks, installing the appropriate ventilation, and using HEPA filters—can reduce their exposure to poisonous dust. We also clarified the difference between asthma and common cold-like symptoms as there were many workers in the dark. They were also very reluctant to accept medical treatment. We also stressed frequent check-ups, smoking cessation, and physical exercise as these are the main steps for maintaining lung health.
At the end of our visit, it was evident that there was no awareness of protection in regard to the protective equipment and hazards at the workplace among workers. Our aim was to fill that void, promote safer practices, and reduce asthma triggers in such hazardous jobs.
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Healthcare

Overview

Studies reveal that asthma causes 1 million annual hospital admissions worldwide. With often preventable conditions leading to an emergency, this phenomenon has motivated us to make hospital visits, and ensure our public outreach to targeted patients. Throughout our visits, we aimed to introduce asthma to different patients to help spread awareness. Among these patients we had a chance to talk to asthma patients, and we listened to their stories about their suffering and burdens. In addition, we got to know about their unmet needs with current asthma medication. Lastly, we handed out our guidebook and poster, which include the steps on using the inhaler and a lifestyle checklist that they can come back to.

We had several discussions with health care providers.We understood that age and mis-education are the main reasons for decreased awareness when it comes to asthma management.These visits did not just spread awareness; they provided us with the insights needed to shape our therapeutic approach to be more patient-centric.

Figure: Pulsatile vs. continuous release
Why it matters
  • Closing the knowledge gap: Our visits clarified asthma symptoms, warning signs, and emergencies, which many patients and families confused with other lung issues.

  • Fixing inhaler misuse: Doctors and pharmacists noted poor technique and non-compliance as key challenges; our demos and visual posters helped patients follow treatment correctly.

  • Listening to patients’ voices: We heard about children left out at school, elders forgetting doses, and adults scared of night attacks. This reminds us that asthma has a strong social impact.

  • Strengthening collaboration: We engaged with both doctors and pharmacists, encouraging them to act as continuous educators, extending the benefit beyond our visit.

  • Driving innovation (PRESS): The feedback from patients and providers inspired PRESS, a solution made to address specific patients’ needs.

Impact on Them

Patients:

  • Gained a clearer understanding of asthma symptoms, causes, and what counts as an emergency.

  • Practiced the correct inhaler technique, lowering mistakes and side effects.

  • Took guidebooks and posters home to share knowledge with their families.

  • Children were taught to carry inhalers at school and alert teachers, allowing them to join in activities safely.

Healthcare providers:

  • Received posters and guidebooks to keep patient education ongoing.

  • Recognized their role as the first line of care in the community.

  • Discussed treatment gaps, confirming the problems of non-adherence and incorrect inhaler use.

  • Shared seasonal trends (like pollen in spring or dust storms in fall) so patients understand what triggers flare-ups.

Impact on Us
  • Human-centered design: Patients’ stories about missing school or struggling with treatment shaped PRESS into a patient-focused solution.

  • Clinical insights: Specialists shared diagnostic challenges and management issues, boosting our medical knowledge.

  • Community linkage: Pharmacies showed us that awareness can spread in everyday community spaces, not just hospitals or schools.

  • Learned how to explain synthetic biology in a simple & reassuring way which improved our science outreach.

  • Discovering seasonal peaks in inhaler use taught us how the environment affects asthma, guiding our educational efforts.

Hospitals

Pharmacies

Hospitals

Throughout February 2025

We visited Abbasiya, Zagazig University, Ibn Sina, Air Force General, and Sidnawy Hospitals, where directors and physicians welcomed us into their respiratory wards. Doctors explained how asthma is diagnosed and its difference from COPD and colds. They were able highlight major asthma challenges such as incorrect inhaler use and poor adherence to treatment.

We met over 864 patients across all age groups. We began our talk with asthmatic patients by asking them about the proper inhaler technique. Turns out that only 23% of patients were using the inhaler correctly. Subsequently, we explained the proper inhaler technique and its significant importance in asthma management.

With children, we discussed how to stay active at school while carrying inhalers. We also shared our asthma child book, and emphasized the importance of seeking help if an inhaler doesn't work. Adults shared daily struggles, which helped us better understand asthma's impact.

We introduced our PRESS as a novel therapeutic approach, showing how synthetic biology could reduce treatment frequency up to once every 12 months. We clarified that our design uses a natural respiratory flora with anti-inflammatory benefits, ensuring safety.

At the end of our visits, our team re-evaluated the asthmatic patients, focusing on their ability to use the inhaler correctly; 98% of them demonstrated proper inhaler usage.

Pharmacies

Throughout August 2025

Pharmacies have a crucial role in our community. They are considered the primary shelter for seeking medical advice or even getting access to medications. Therefore, we visited local pharmacies to introduce our therapeutic approach and highlight their role as community health hubs. We shared our asthma guidebook and asked to display posters on proper inhaler use, which pharmacists welcomed and even requested extra copies for patients.

Pharmacists explained that inhaler demand spikes twice a year—spring (pollen) and autumn (dust storms). This confirmed common allergen triggers in our community and shaped our educational materials.

6 months later, we conveyed follow-up visits to these pharmacies. Pharmacists reported that over 650 proper inhaler technique posters were taken by asthma patients, and they requested more copies.

By collaborating with pharmacists, we ensured wider patient access to guides regarding accurate inhaler techniques, created a sustainable channel for awareness, and built stronger trust around our project's relevance.

Family

Asthma is very common in children. Since they spend most of their time at home with their families, we have created educational materials that target both children and parents. We also included simple lifestyle tips that can help prevent and manage asthma. This is clearly represented in the following materials:

Songs

Child book

Parentsidebook

Pet waste management poster

PET waste management Poster


Instructions: Player should avoid dust, smoke, cigarettes & cat dander, while trying to collect the inhalers.

Game

Asthma Hero Run

Help protect yourself by avoiding triggers...

High Score: 0

Use ARROWS or W/S to move.

Collect for a shield!

Select Difficulty

How Education Shaped PRESS

Kindergarten & Primary Students

Structure Prediction

Explaining asthma with songs and play reminded us that science must be simple and relatable. PRESS should be designed as a therapeutic approach that patients and families can easily understand and trust.

Preparatory Students

Structure Prediction

Their struggles with DNA and mutations showed us the need for transparent, easy-to-grasp communication about gene editing and safety. This shaped how we present PRESS as a safe and responsible therapy.

Secondary & STEM High School Students

Structure Prediction

Their questions about treatments and side effects pushed us to highlight why PRESS is safer, fewer side effects and longer-lasting compared to competitors. It reinforced our choice of a 1–2 doses/year design.

University Students

Structure Prediction

Working with plasmid design and biosafety reminded us that PRESS must stand on strong scientific and ethical foundations. It shaped our approach to include regulation, validation, and lab safety at every step.

Geriatrics

Structure Prediction

Older patients shared struggles with memory lapses, weak grip, and side effects. This confirmed the value of PRESS as a patient-friendly approach with fewer doses once every 6-12 months, easier use, and action targeted to reduce systemic risks.

Public Outreach

Structure Prediction

Listening to public fears about synthetic biology showed us that acceptance matters as much as efficacy. This guided us to explain PRESS through familiar biotech examples like insulin, probiotics, and vaccines

Hospitals & Healthcare Providers

Structure Prediction

Doctors and patients pointed out that non-adherence and poor inhaler technique remain major barriers. This reinforced PRESS as a long-acting therapy designed to overcome daily-use problems.

Pharmacy

Structure Prediction

Pharmacists showed seasonal asthma peaks (spring pollen, autumn dust storms). This gave us insight into when PRESS would be most impactful and highlighted the need for strong community awareness.

Policy Makers

Structure Prediction

Talking with policy and industry leaders showed us that innovation must also meet regulatory, manufacturing, and market standards. Their input helped us plan PRESS as not just a concept, but a realistic, patient-ready product.

Summary

What was your educational goal, and who was your target audience?
  • Our main goal was to spread awareness about asthma across community and high risk groups especially and introduce synthetic biology in a way that connects both science and real-life health.

  • We designed a full age timeline (from Kindergarten to Policy Makers), showing how content evolved with each audience’s capacity.

  • Kindergarten: focus on understanding asthma through play, songs, and simple visuals. Define different body parts with stressing on team work skills.

  • Primary & Preparatory: introduce biology basics, DNA structure,Microbes, and research thinking through games and experiments. The team also aimed to introduce lung structure and mention proper inhaler techniques in an easy simple way.

  • High School: explain gene expression, siRNA, and entrepreneurship concepts.The team also mentioned current asthma medications and types of inhalers.

  • University: train students on molecular tools (Benchling, plasmid design, ethics).

  • Adults & Geriatrics: discuss asthma management challenges and daily health.

  • High risk Groups: visited occupations that pose a high risk of asthmatic triggers in order to raise awareness.

  • Policy Makers: open dialogue on synthetic biology and education inclusion in curricula.

How did you design your education activities?
  • Activities were built around two main tools we created for clarity and structure:

    • Page Style Tool → organizes the Education page into four main parts (Journey, How Education Shaped PRESS, Focused Outreach, Feedback).

    • Event Documentation Tool → defines five consistent elements (Overview, Why it matters, Activities, Impact on Us, Impact on Them).

  • These tools were inspired by scientific learning models:

    • Kolb’s Experiential Learning Cycle (experience → reflection → application).

    • Inquiry-Based Learning (question-driven discovery).

    • Community-Based Participatory Research (mutual learning).

  • This framework made every event evidence-based, structured, and comparable.

How did you ensure your activities were effective and age-appropriate?
  • KG events:

    • Used role-play.

    • Added an inhaler song with step-by-step technique.

    • Posters + coloring activities reinforced learning visually.

  • Primary & Preparatory :

    • Card games and colored DNA models simplified genetic code and mutation.

    • Role-play showed the central dogma (DNA → RNA → Protein).

    • “Scientific research cycle” activity built early critical thinking.

  • High School :

    • Introduced gene expression & synthetic biology through interactive card simulation (DNA–RNA–protein–siRNA).

    • Connected directly to PRESS (TSLP gene, inflammation control).

    • Included short intro to entrepreneurship cycle (problem, gap, USP).

  • University & STEM

    • Live demo using Benchling plasmid map; explained promoters, resistance markers, and gene cloning.

    • Shared dry-lab ethics checklist (biosafety, data privacy, IPR).

  • Public & Geriatrics

    • Gave practical lifestyle advice, discussed drug side effects and adherence.

    • Engaged in dialogue to understand fears of aging patients & synthetic biology myths.

  • Policy Makers:

    • Discussed integrating our SynBio Guidebook into the medical curriculum as an elective course.

    • Exchanged feedback on ethical approval and curriculum adaptation.

How did you evaluate learning outcomes or impact?
  • Used both quantitative and qualitative evaluation:

    • Pre/post quizzes

    • Collected verbal feedback and reflection from participants.

    • Observed behavioral improvements (students using inhalers correctly, better understanding of asthma management).

  • Each event ends with a reflection on how students or participants retained the information and applied it.

  • Graphs and data are included visually to show measurable improvement.

How did your education efforts connect to your iGEM project (PRESS)?
  • Education was not separate — it directly shaped PRESS design and focus.

  • Feedback from geriatrics → inspired longer dosing interval (6-month formula).

  • School and student feedback → highlighted misunderstanding of inhaler use → reinforced need for accessibility and safety.

  • Policy discussion → emphasized regulatory and ethical clarity in biotherapeutics.

  • University sessions → refined our internal lab safety and data ethics approach.

  • The “How Education Shaped PRESS” section summarizes this evolution through all stages.

How did you make your materials reusable and accessible?
  • Shared all educational content online:

    • Asthma child book, inhaler posters, songs, SynBio Guidebook, Benchling templates, safety checklists.

  • Visuals and handouts are easy to translate and adapt for other regions or teams.

  • The two tools (Page + Event) are open frameworks for future teams to document and teach effectively.

  • All materials are hosted on the wiki and social media to encourage reuse.

How did you ensure responsibility, ethics & inclusivity?
  • Collaborated with physicians (Dr. Doaa – School Physician, Dr. Wagida) to ensure accuracy and safety.

  • Activities supervised in safe environments with real medical models (placebo inhalers).

  • Language accessibility: materials available in Arabic, English, Chinese, and Greek.

  • Considered vulnerable groups: geriatrics, children, and asthma-risk workers.

  • Addressed misinformation about inhaled steroids and synthetic biology ethics during sessions.

How did you create dialogue and mutual learning (not one-way teaching)?
  • Every session included Q&A and two-way discussion:

    • KG students shared what they learned with family → reinforcing memory through social sharing.

    • High schoolers questioned gene editing ethics → led us to strengthen communication on biosafety.

    • Geriatrics shared medication challenges → shaped our product adherence plan.

    • Society Club discussions corrected synthetic biology misconceptions, turning skepticism into curiosity.

  • Policy meetings encouraged bidirectional exchange between our team and regulatory bodies.

  • Every meeting has two sections ( impact on us - Impact on them ), containing the detailed mentions of the two way discussion.

What is the lasting value of your education work?
  • The dual-tool framework (page + event) converts educational reporting into a repeatable, scientific documentation method.

  • Materials (songs, visuals, guidebooks, datasets) remain publicly available for future iGEM teams.

  • Our structure supports evidence-based learning, transparency, and reflection — a sustainable education model within iGEM.

  • By linking every stage to real-world health and innovation, we built a legacy that blends scientific education with community empowerment.

References

Click to view
  • Vandenplas, O. (2011). Occupational asthma: Etiologies and risk factors. Allergy, Asthma & Immunology Research, 3(3), 157–167.

  • Jaakkola, M. S., Lajunen, T. K., Heibati, B., Wang, Y.-C., Lai, C.-H., & Jaakkola, J. J. K. (2021). Occupation and subcategories of asthma: A population-based incident case–control study. Occupational and Environmental Medicine, 78(9), 661–668.

  • Dodd, K. E., & Mazurek, J. M. (2016). Asthma among employed adults, by industry and occupation—21 states, 2013. Morbidity and Mortality Weekly Report, 65(47), 1325–1331.

  • Nayak, S., Dash, S., Shahu, S., Chavhan, S., & Dambhare, D. (2023). Assessment of pulmonary function test in brick factory workers. Journal of Family Medicine and Primary Care, 12(2), 213–220.

  • Rose, C. S., Heinzerling, A., Beebe Ortiz, C., Macphail, K., Fagan, K., Matias, W., Begay, J., Torre, F., Mroz, M., Reynolds, E., Wolff, J., Hoffman, S., Ham, J., & Nett, R. J. (2021). An outbreak of work-related asthma and silicosis at a US countertop fabrication facility. American Journal of Industrial Medicine, 64(12), 1046–1052.

  • National Institute for Occupational Safety and Health. (1997). Preventing asthma in animal handlers (DHHS (NIOSH) Publication No. 97-116).

  • The Global Asthma Network. (2022). The Global Asthma Report 2022 [PDF]. International Journal of Tuberculosis and Lung Disease, 26(Supplement 1), S1–S102.

  • Kolb, D. A. (1984). Experiential learning: Experience as the source of learning and development. Englewood Cliffs, NJ: Prentice-Hall.

  • Kolb, D. A. (2015). Experiential learning: Experience as the source of learning and development (2nd ed.). Pearson Education.

  • Muhammad, M., Dickson, E., Alaniz, C., & Wallerstein, N. (2021). Understanding community-based participatory research across four dimensions: Theory, pedagogy, research, and praxis. In Community-Centered Public Health: Strategies, Tools, and Applications for Advancing Health Equity (pp. –-). Springer Publishing

  • Evidence-Based Research Network. (2020). Evidence‐Based Research Series – Paper 1: What Evidence‐Based Research is and Why Is It Important? Journal of Clinical Epidemiology, 123, 162-168.

  • Pearson. (n.d.). Inquiry-Based Learning: Practices that Foster Effective Learning [PDF].

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