Specific Session Contents and Outcomes
1. Learning Fundamental Techniques and the History of Evolution
The sessions began with an explanation of the traditional foundational technologies of synthetic biology, such as restriction enzymes, plasmids, and transformation. We further emphasized the utility and future potential of the innovative CRISPR/Cas9 genome editing system, which has become essential in modern microbiology research, thereby encouraging the students' understanding of the rapid developments in life science.
2. Discovering "Questions" Through iGEM Projects
Using past iGEM projects as case studies, we discussed not just the technology itself, but also the creativity and challenges inherent in scientific frontiers.
Medical Applications
We introduced PekingHSC's project, "Curmino," a drug delivery system for cancer using E. coli. Through discussions surrounding the project's innovativeness and the problems yet to be solved, students gained a sense of the difficulty involved in creating something new and useful.
Innovation in Research Methods
We presented Heidelberg's "PiCasSO," explaining the groundbreaking aspect of synthetic biology—that it can create new research tools themselves.
3. Real-world Implementation and Contribution to a Sustainable Society
To help students understand the broad scope of synthetic biology applications, we highlighted real-world startup companies and their social impact.
Apparel/Materials
Spiber, which develops durable and sustainable fibers from spider silk.
Agriculture/Environment
Pheronym, which utilizes nematodes for a new form of pesticide that reduces health hazards and environmental load.
Through these diverse examples, students deepened their recognition that synthetic biology is indispensable for achieving a sustainable society (SDGs) and is a discipline that directly contributes to solving societal challenges.
Summary
This educational activity demonstrated that synthetic biology is a unique academic field combining both "Engineering" and "Biology," giving the students a strong interest and deep insight into the next-generation bio-revolution.Throughout the entire session, the participating high school students comprehensively learned topics ranging from fundamental knowledge to cutting-edge technology and social application examples. Especially by promoting participatory discussions, they were able to deepen their recognition that synthetic biology is an academic field with interdisciplinary appeal and an indispensable role in achieving a sustainable society (SDGs).
