Education

Introduction


In the wave of the 21st century, biology is booming at an unprecedented speed and has become a key force in driving the progress of the world. However, synthetic biology, this highly potential frontier field, is still little known to many people. In our school, there are many curious students eager to explore the mysteries of synthetic biology, but they have little to no opportunity to do so. Looking at the global level, even more people know little about the concept and application of synthetic biology, and in the field of space exploration, which is full of unknowns and challenges, the application of synthetic biology is even less known.


As a public welfare organization committed to promoting science education and innovation, we feel a great responsibility. We hope that through our efforts, more people can truly understand synthetic biology, unveil its mysterious veil, and feel its endless charm. At the same time, we also hope that more people can understand our projects and witness how we combine the theory and practice of synthetic biology to contribute to solving real-world problems and expand the boundaries of synthetic biology through our projects.

Our Goal

As a synthetic biology team, we strive to make a difference through education. First, we aim to demystify synthetic biology, making its concepts accessible to all. Second, we want to spotlight our projects, showing how they bring synthetic biology to life and address real-world challenges. And how do we expand the boundaries of synthetic biology through our projects.


Education on Social Media


We have come to deeply understand the importance of social media in promoting synthetic biology and iGEM projects. Therefore, we have established our own accounts on mainstream Chinese media platforms, including Xiaohongshu, Bilibili, WeChat Video Channel, and WeChat Official Accounts. Through these platforms, we share content on synthetic biology from previous years and demonstrate experimental procedures to promote a broader understanding of the field.


WeChat Official Account for Synthetic Biology Popularization

Bilibili Account for Synthetic Biology Education

Xiaohongshu Account for Synthetic Biology Popularization

To date, our efforts have been met with positive responses, and we have garnered over 100 followers and more than 1,000 views across our channels. This growing engagement highlights the effectiveness of our approach and motivates us to continue creating valuable content to reach even more people.


Introducing Synthetic Biology to Students


Survey


Survey Result: Willingness to Attend Synthetic Biology Lectures

After surveying the majority of students in our school, we found that a large majority of them are eager to learn about synthetic biology but have little to no opportunity to do so. Many expressed a keen interest in attending lectures on the subject.


Therefore, we hope to bring synthetic biology to life for students by sharing the stories of our previous SHSBNU iGEM projects. Through these real-world examples, we aim to make the learning experience more engaging and relatable. In addition to the lectures, we also provided opportunities for the students to participate in hands-on experiments. This hands-on approach allows them to see the practical applications of synthetic biology and gain a deeper understanding of the subject.



Lecture


The Second High School Attached to Beijing Normal University (Lecture Venue)

The Second High School Attached to Beijing Normal University (Lecture Hall)

We designed three lectures on “previous synthetic biology projects” and held them on September 1st, 5th, and 15th, each lasting one hour. During these sessions, we showcased models of our past project designs, which were safely created using 3D printing to illustrate key concepts. We encouraged students to ask questions about these models, and we were there to clarify any doubts they had. This hands-on approach helped them see how synthetic biology can be applied in various aspects of life. Each lecture attracted over 70 participants, accounting for 75% of the entire grade 10 student body.


Lecture presentation 1 PDF:


Lecture presentation 2 PDF:


Lecture presentation 3 PDF:


Offline Experience Activities


In addition to the lectures, we also organized other activities to give students a taste of synthetic biology experiments. We taught them the basics, such as how to use a pipette accurately. These hands-on experiences helped them get a feel for what working in a synthetic biology lab is really like.




Feedback


Before



1. How Do You Understand Synthetic Biology?
Using the reverse thinking of traditional biology, designing and reconstructing biological components to create new systems; well... it is combining the principles of engineering with biotechnology to solve issues such as environmental resources.
Synthetic biology is a discipline that builds components from the most basic elements, following a bottom-up approach.
It is the study of organisms in nature.
My understanding of synthetic biology is feeding various cells and microorganisms with extremely low-cost feed; it is an interdisciplinary field that uses knowledge from multiple disciplines to compose new DNA and realize the modification of organisms.
I understand synthetic biology as using known existing genes of organisms to modify and synthesize new organisms; by changing the genes of organisms, we can alter some traits of organisms to benefit humanity.
I think synthetic biology enables organisms to possess specific abilities by designing, modifying, or synthesizing their genes; it combines biology, engineering, computer science and other disciplines to edit the genes of organisms.
A cutting-edge discipline based on molecular biology that modularizes genetic engineering design.
As a branch of biology, it mainly studies basic elements to establish artificial biological functions.
It is related to genetic engineering and materials, and solves life science-related problems through biological and interdisciplinary practices.
I believe synthetic biology uses existing technologies and materials to redesign and combine into new substances to achieve functions that raw materials cannot achieve; it is of great value to human development and valued by the country, integrating biology, engineering and other disciplines related to genes.
Based on some information I have searched, synthetic biology seems to have interdisciplinary characteristics, requiring the ability to master multiple disciplines to do it well.
Solving practical problems through (biological extraction?) artificial synthesis of macromolecular substances.
2. How Do You Understand iGEM?
A platform for showcasing new ideas in synthetic biology, where experts from around the world gather to communicate and make progress.
A competition that tests teamwork, promotes the development of synthetic biology, and cultivates innovative talents.
A competition that requires participants to assemble artificial biological systems and conduct manipulation and measurement.
A very excellent club.
iGEM is the abbreviation of International Genetically Engineered Machine Competition, a team competition. Team members are divided into dry teams and wet teams: dry teams are mainly responsible for web design, etc., while wet teams are mainly responsible for conducting experiments and recording experimental data. There is also a defense session in the official competition, which requires introducing the cutting-edge nature of the project and answering questions from judges.
The International Genetically Engineered Machine Competition, which involves knowledge related to synthetic biology.
A competition for technological innovation using biological knowledge.
Well, I understand iGEM as a biological competition for high school and college students. I think its relationship with synthetic biology is promotional: synthetic biology can be used in various fields, while iGEM focuses on conducting experiments on specific topics to be explored, and student teams conduct research.
It is a top competition in synthetic biology with authority, testing students' abilities beyond just biological knowledge; it constructs functional biological systems that can solve life problems, contributes to synthetic biology, exercises scientific research capabilities and teamwork skills, and enhances knowledge and self-improvement.
The International Genetically Engineered Machine Competition, hosted by the Massachusetts Institute of Technology (MIT), is a top competition in the field of synthetic biology. Its core is to answer whether synthetic biology operations can be completed in living cells through competition.
Based on synthetic biology, it inspires participants to provide well-being to human society through synthetic biology technology in the form of project-based competition.
A well-known large-scale competition related to synthetic biology.
An innovative competition related to synthetic biology that also solves problems through genetic engineering and interdisciplinary approaches.
I understand iGEM as a global showcase platform and also a high-level competition in the biological field, demonstrating students' design capabilities, innovation capabilities and teamwork capabilities.
An international top-level large-scale synthetic biology competition that promotes interdisciplinary integration and cultivates students' creative thinking.
An international competition in synthetic biology, which, like synthetic biology, has interdisciplinary characteristics.
The International Genetically Engineered Machine Competition, which is very authoritative.

What is Synthetic biology?

“Synthetic biology is the study of living organisms in nature.”

“As a branch of biology, it is a discipline that mainly studies basic elements to establish artificial biological functions.”

“Based on some information I have gathered, synthetic biology seems to have an interdisciplinary nature and requires the ability to master multiple disciplines to do well”


What is iGEM?

“A competition that requires participants to assemble artificial biological systems and perform manipulation and measurement”

“An international competition in synthetic biology, like synthetic biology, has the characteristic of being interdisciplinary”


Prior to engaging the students in hands-on experiences, we collected their initial perceptions of synthetic biology and iGEM. It was interesting to see that there was a notable discrepancy between their understanding and the actual essence of these fields. The majority of students associated synthetic biology solely with “genes” and saw iGEM as just “a competition”.



After


Changes in Understanding of Synthetic Biology and iGEM (After the Activities)
I never thought synthetic biology could also be applied in fields like space, which surprises me.
I originally thought it was just a competition based on experiments and thesis defense, but I never expected it could also incubate real biotech companies—I find it very interesting.
Using Gibson assembly to join different gene fragments into one gene fragment so that E. coli can produce the gene fragments needed for experiments.
What is the working principle of a fermenter? For example, how does it measure the conditions inside the tank in real time?
I think the most basic aspect of synthetic biology is the need to standardize the modification of biological components such as proteins so that they can (function properly).
iGEM tends to focus on a large number of practical experiments and the analysis of experimental data, which is different from knowledge-based competitions (iGEM seems to have the meaning of “learning by doing”?).
Extract the supernatant. (Note: Experimental operation description)
Insert several segments of genes into E. coli to synthesize theanine.
How to synthesize DNA? Synthetic biology is about inserting desired genes into microorganisms.
Identify research topics, synthesize substances using synthetic biology methods, and prove their feasibility.
It’s surprising that theanine can relieve anxiety.
Synthetic biology can create genes.
It is a research conducted by a team of several people on solving new problems related to synthetic biology, and the research finally needs to be reported to the judges.
I think the heart valve project is particularly interesting.
I feel it’s not as “high-end and unreachable” as before.
At first, I thought iGEM was just a boring and single-purpose project aimed at competing every year. But after listening to the Tencent Meeting introducing iGEM a few days ago, I realized that iGEM projects actually originate from solving real-world shortcomings and use synthetic biology technology to benefit humanity. It really feels very meaningful. If my initial motivation to join iGEM was to add something to my resume, now I truly want to use my knowledge to personally create something useful and benefit others.
I will look for practical tools; those projects related to protein synthesis truly use amino acids to form proteins for observation; some projects are based on proteins during the experimental process and create solutions for problems in different fields such as spacesuits and valves.
I found that the scope of these experiments is very broad.
The iGEM club carries out the first step of innovation—it only conducts the first step of testing to see if a project is feasible, rather than directly applying it to clinical experiments in life within our club.
Theanine has a refreshing effect.
How to turn the microscopic structure of protein chains into visible protein filaments with that strange small machine?
Basically understood the experimental methods and concepts of synthetic biology, and understood the general process of experiments and competitions.
A platform that provides new ideas for the technological development of human society.

How do you all understand synthetic biology now

“I initially thought iGEM was just a boring and singular project aimed solely at competing each year. However, after attending the iGEM introduction on Tencent Meeting, I realized that iGEM projects are actually rooted in addressing real-world deficiencies and using synthetic biology to benefit humanity. It feels incredibly meaningful. While my initial motivation to join iGEM was to add something to my resume, now I genuinely want to use my knowledge to create something useful and make a difference.”

“I thought this was just a competition based on experiments and thesis defenses. I never expected that it could also incubate real biotech companies. I think it's very interesting

“I will look for tools for practical operation. Those projects related to protein synthesis are all truly composed of amino acids to form proteins. Some projects are based on proteins during the experimental process and create for problems in different fields such as aviation suits and valves”


Cooperation with Other iGEM Teams


CCiC


CCiC presentation PDF:


CCiC Conference: Project Presentation

During these interactions, we emphasized the importance of our fermentation apparatus, which is designed to significantly increase bacterial yield. We explained how our device not only keeps the bacteria alive but also optimizes growth conditions to maximize productivity. This innovation was a key focus of our project, and the feedback from other teams in CCiC confirmed that such a device is highly needed in the field. Their interest and positive feedback further motivated us to refine and perfect our fermentation apparatus, ensuring it meets the needs of researchers and practitioners alike.



SHSBNU x JLU


Cooperation Discussion with Jilin University iGEM Team

We engaged in a detailed discussion with Jilin University. They expressed high recognition and appreciation for our project. They were particularly impressed with how we incorporated project presentations into our educational activities. They highlighted that this approach is not only a novel method of education but also an effective way to attract a larger audience. They noted that by sharing real-world applications and engaging students through interactive sessions, we were able to make synthetic biology more accessible and appealing to a broader group of students. This method not only educates but also inspires, encouraging more students to explore the potential of synthetic biology in solving real-world problems.



SHSBNU x TJU


Cooperation Exchange with Tongji University iGEM Team

Through communication with the team from Tongji University, they expressed great admiration for our creative ideas. They conveyed their belief that our project has the potential to become a reality in the future. They also highlighted that our project might not only be applicable in the near future but could also have significant implications and applications in the distant future.


In our exchanges, both our teams are exploring the limits of synthetic biology applications. We are working to expand the scope of synthetic biology and promote it through our efforts.



SHSBNU x BNDS


Cooperation Dialogue with BNDS iGEM Team

In our interactions with the BNDS team, they praised our project for its imaginative and ambitious nature. They acknowledged that our efforts to pioneer new application areas for synthetic biology not only push the boundaries of the field but also offer fresh perspectives for their projects in the coming years. Additionally, they highly commended our lectures for highlighting previous projects as an innovative theme, appreciating how this approach effectively conveyed the evolution and impact of synthetic biology.



SHSBNU x KEYSTONE x BNDS x RDFZ x UCAS x BJWZ


Multi-Team Cooperation Exchange (SHSBNU, KEYSTONE, BNDS, RDFZ, UCAS, BJWZ)

In a collaborative exchange involving SHSBNU, KEYSTONE, BNDS, RDFZ, UCAS, and BJWZ, our project received high praise from the other teams. Notably, several undergraduate students from UCAS complimented our project, saying, "The application prospects of this protein glue are extremely broad, and the project is exceptionally well done." Our efforts have provided new application scenarios for synthetic biology, inspiring other teams to further expand the scope of its applications.