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"Art is the eternal science, and science is the transformative art."

— James McNeill Whistler

Introduction

Inspired by James McNeill Whistler’s opinion of the relationship between art and science as an active force, our work in Human Practices is grounded in the conviction that art should not merely reflect the world—it must actively reshape it. Through synthetic biology, we move beyond representation into creation, turning living cells into brushes and light into a medium of expression.

As an endeavor spanning artistic, scientific, and social dimensions, bioart demands a holistic and inclusive approach. To ensure our project resonates across disciplines and cultures, we have engaged diverse voices and perspectives, structuring our Human Practices around a reflective and adaptive framework. Guided by this ethos, we strive not only to reimagine the boundaries of art but also to build bridges between laboratories, galleries, and communities—transforming how society sees, creates, and values life itself.

Stakeholder Interaction

Our stakeholder analysis is conceived not as a chart, but as a living tapestry, woven from the many voices that shape our bioartistic endeavor. Like light passing through a prism, our project is refracted through diverse perspectives:

  • From the foundational light of synthetic biologists and researchers, to the clarifying focus of application specialists.

  • Through the interpretive lenses of curators and artistic professors, and the creative visions of bioartists themselves.

  • It culminates in its reception by the public and art lovers, where the work truly comes to life.

This layered, flower-like framework embodies our core conviction: that art, in collaboration with science, does not merely observe the world, but actively composes it. Each layer is essential, interweaving to transform how we see, create, and value life itself. You can see more details in our Implementation.

Bioartists

as

Art & Science Research Center

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The Art & Science Research Center

the Art & Science Research Center: It is a non-profit organization with "driving change through interdisciplinary innovation" at its core. The center integrates creation and communication, leveraging cutting-edge technologies and pioneering artistic thinking to promote public engagement with science and foster deep collaboration across diverse fields. This time we are honored to have an in-depth conversation with its founder,Professor Cai Xiao and her student Liu.

Cai Xiao: Director of the Living Lab at the Central Academy of Fine Arts School of Design and founder of the Art & Science Research Center. Having curated numerous sci-art exhibitions, they are also the author of several acclaimed works including The Incomplete Body Manual,and Micro-Imaginaries: A Scientific and Artistic Journey with Bacteria.

Reflect

Through in-depth collaboration with the Art & Science Research Center, led by Professor Cai Xiao, we have refined the project's innovative direction—centered on "illumination-guided bacterial painting", which merges synthetic biology with artistic expression. We have further articulated a dual narrative architecture where art and science advance in parallel, while gaining valuable insights into technical execution and presentation methods. The AS Center emphasized the importance of grounding science communication in public understanding, using visual storytelling and risk assessment to build trust. Overall, the project embodies both experimental rigor and artistic sensibility, though nuances such as layered color control and public engagement call for further refinement.

What we want to know

1. How can we more intuitively convey the technical aspects and significance of the project to non-specialist audiences?

2. Are there optimal cases for visualizing microbial safety?

3. How might the venue conditions of an offline exhibition affect the presentation of the bacterial artwork?

Renew and record

  • 1. On Public Engagement

    Professor Cai emphasized that science communication should begin with concepts familiar to the public, using metaphors or engaging topics to capture attention. In this project, the technology of light-controlled gene expression can be likened to a "biological printer" or "living pigment factory" , where light directs E. coli to produce specific colors. This approach not only represents an artistic innovation but also highlights the potential of synthetic biology in sustainable manufacturing, potentially enabling eco-friendly production of dyes and pigments in the future. Framing the project within broader themes like "bio-printing" or "green manufacturing" can help the public appreciate both the phenomenon and its scientific significance.

  • 2. Strategies for Safe Exhibition

    Building public trust is essential, and concerns about microbial safety can be addressed through rigorous risk assessment and visual demonstrations. It is important to emphasize that the engineered E.coli strains used are non-pathogenic and highly safe, akin to "domesticated microbial factories." Visually, infographics or animations can illustrate dual safety measures—both physical and biological. Such presentations help viewers "see" the safety mechanisms in place.

  • 3. Impact of Exhibition Environment on Artistic Outcome

    The key factors affecting the presentation are lighting and temperature/humidity.

    Since color production relies on precise RGB light control, ambient exhibition lighting (especially natural or stray artificial light) may interfere with the programmed illumination, affecting color accuracy and saturation. A controlled lighting environment, possibly involving darkened spaces or localized shading,is necessary.

    Temperature & Humidity directly influence bacterial activity and hydrogel stability. Unsuitable conditions may disrupt the painting process or compromise detail preservation. An ideal venue should provide a stable, controlled environment, a critical consideration when using hydrogel as a carrier medium.

How we take responsibility&response:

  • Continue to assess the feasibility of the project in terms of legal compliance, timeline, socioeconomic impact, and technical risks

  • Design interactive sessions during the exhibition to alleviate public concerns about microbial art and build trust

  • Explore the implementation of multi-layered canvas effects to achieve color stacking reminiscent of oil paintings

  • Investigate potential avenues for integrating artificial intelligence technology with the project

Prof. Yun Yang

Bio-art course

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Prof. Yun Yang

Bio-art course Lecturer for the Singularity Biotechnology and Life Arts research course School of Medical Science and Engineering, Beihang University

Research Interest

Synthetic Biology

Reflect

After consulting with Professor Yang, we reviewed our project theme and examined how its content aligned with the concept. The course model of "Singularity Biotechnology and Life Art" further inspired us to develop a dual-narrative approach that intertwines art-bio and bio-art perspectives.

What we want to know

  • The current condition of biological art related courses in domestic education

  • Key factors to ensure the project has a lasting social impact

  • How to better integrate science and art into education

Record&Renew

During the exchange, Professor Yang introduced the background, student composition, and teaching model of the "Singularity Biotechnology and Life Art" course. This course is part of Beihang University's first-class undergraduate curriculum initiative and a community-based program in Beijing's Xueyuan Road area. It covers students from diverse academic backgrounds including art disciplines (such as new media and visual design), biomedical engineering, foreign languages, and students from multiple universities in the Xueyuan Road region. The course welcomes students from all academic backgrounds, focusing on cultivating innovative thinking that integrates science and art. In terms of teaching methodology, we learned that the course interprets life sciences through dual perspectives of science and art, concluding with practical life experience sessions to reinforce the "art-inspired truth" mindset. This complementary narrative approach across disciplines also provides valuable inspiration for constructing a "dual-line narrative" framework.

Furthermore, Professor Yang noted that as the life sciences framework continues to evolve, artistic thinking in life sciences not only drives innovative discoveries but also facilitates the distillation of fundamental biological principles from vast knowledge. The future of life sciences education is transitioning from mere knowledge transmission to an integrated approach that combines artistic perception with ethical considerations.

Professor Yang proposed several project recommendations:

  • 1.Consider the depth of project content by enhancing the alignment between experimental design and thematic focus through specific feature matching, highlighting the project's unique characteristics – this is a key factor in ensuring sustained project impact.

  • 2.Emphasize the theme through contrast. Utilize light and shadow effects, or create distinct visual compositions for three color lighting scenarios to embody Zen philosophy.

Bioartists

Daosheng Synbiology

Bio-indigo Producing

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Daosheng Synbiology

Bio-indigo Producing

Centered on the concept of a "microbial cell factory," synthetic biology has been employed to engineer E.coli into an "indigo cell factory." Through cross-species gene recombination, AI-driven metabolic regulation, and green purification processes, high-purity bio-indigo (40g/L) is mass-produced in a 10kL fermenter within just three days. The color fastness rivals that of chemical indigo, while wastewater and carbon emissions are reduced by over 80% each. This technology has now been extended to the full spectrum of natural pigments, including black and red bio-pigments, and is gradually expanding into applications in food, cosmetics, and pharmaceutical intermediates.

Reflect

After the interview, we identified the reasons for the color change of indigo pigment and found a better way to preserve indigo. Under the guidance of Professor Liu, we gained a deeper understanding of the dyeing ability and process of indigo. Simultaneously, we optimized the extraction and concentration determination methods of indigo, laying a reliable foundation for the subsequent experiments on purple and green pigments, and enhancing the team's confidence in pigment fermentation.

What we want to know

  • How to maintain the stability of indigo pigment

  • The methods for extracting indigo and calibrating its concentration

Renew and record

In response to our questions, Professor Liu provided the following guidance on pigment extraction and storage:

  • 1.Pigment storage

    Indigo pigment must be stored away from light, as light exposure can accelerate its degradation. During fermentation, bacteria not only produce indigo but also indirubin. Thus, the reddish tint sometimes observed in our experiments is likely due to the higher stability of indirubin compared with indigo, causing indigo to degrade while indirubin persists.

  • 2..Determination of pigment concentration

    High-performance liquid chromatography (HPLC) is the preferred method. If equipment is limited, ultraviolet-visible spectrophotometry or a microplate reader are excellent alternatives. In industrial production, chemical titration is also commonly employed for concentration assays.

  • 3.Choice of fabric for dyeing

    Commercially available cotton, linen, and silk fabrics are all highly suitable for indigo dyeing.

  • 4.Dyeing considerations

    Indigo extracted from plants achieves excellent coloration at concentrations of only 1–2 %. Therefore, there is no need to pursue excessively high pigment concentrations. After dyeing, the fabric should likewise be protected from light to maintain color stability.

SYNBIO TECHNOLOGIES

Synthetic Biology company

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SYNBIO TECHNOLOGIES

Synthetic Biology company

The company is committed to becoming a leader in synthetic biology enabling technologies, offering integrated solutions for the "Design-Build-Test-Learn" DNA cycle. Its business spans sequence intelligent design, gene synthesis, protein expression, gene editing, and more, serving fields such as life sciences and DNA data storage.

Reflect

Following the discussion, we recognized that while the promoter replacement strategy is theoretically viable, it requires further experimental verification. For the dual-promoter co-expression system, parallel control experiments should be designed to evaluate performance, with attention to reducing inclusion bodies by lowering the temperature. Furthermore, the issue of faint small-fragment marker bands can be mitigated by optimizing electrophoresis conditions. It is also advised to apply multi-plasmid expression systems with fewer genes per vector and perform stepwise validation to enhance overall expression efficiency and experimental reliability.

What we want to know:

  • Feasibility of Promoter Replacement Methods

  • Optimization of Co-expression in Green Light-Controlled Systems Molecular

  • Specific Issues regarding Experimental Operations

Renew & Record

During the initial experimental phase, we sought technical support from Professor Wang at Hongxun Biotechnology. Key points discussed include:

  • 1. We plan to use homologous recombination and inverse PCR to replace the IPTG-induced T7 promoter with a light-controlled PhlF promoter for independent validation of indigo synthesis before coupling it with the optogenetic system. While theoretically feasible, this method lacks established precedents.

  • 2. For the green-light control system, using separate promoters for mini-CcaS and CcaR may affect their interaction. Parallel controls were suggested: one using two promoters, another with a shared promoter. However, comparing effectiveness is complicated by potential differences in promoter strength and possible inclusion body formation, which might be mitigated by lowering the transformation temperature.

  • 3. Faint marker bands below 1000bp may result from small bands migrating too far or overloading of sample DNA. Solutions include shortening electrophoresis time, increasing marker loading, or reducing sample volume. Unclear markers in blank regions do not affect results.

  • 4. Given that current constructs carry multiple genes on few plasmids—possibly affecting expression—using separate plasmids for each gene could improve results, despite lower co-transformation efficiency. Alternatively, stepwise validation of individual genes is recommended.

How we take responsibility&response

In subsequent designs, we found that homology recombination was unnecessary for promoter replacement. By utilizing restriction sites upstream of the T7 promoter and careful primer design, we successfully removed the T7 promoter via enzymatic digestion and directly inserted a light-controlled promoter.

Following the reference paper, we expressed mini-CcaS and CcaR using two separate promoters—identical to those in the publication—on a single plasmid Such issues rarely occurred in later experiments, and cases that did not affect the results were disregarded.

For multi-gene delivery, as exemplified by the green light-controlled system, we divided the experimental process into two parts:

  • Directly introducing a plasmid containing all genes and validating protein expressio

  • Performing separate PCR amplification for each gene, cloning them into individual plasmids, and transforming them into different E.coli  strains to verify the expression of each gene independently.

Daosheng Synbiology

Bio-indigo Producing

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Daosheng Synbiology

Bio-indigo Producing

Centered on the concept of a "microbial cell factory", synthetic biology has been employed to engineer E.coli into an "indigo cell factory". Through cross-species gene recombination, AI-driven metabolic regulation, and green purification processes, high-purity bio-indigo (40g/L) is mass-produced in a 10kL fermenter within just three days. The color fastness rivals that of chemical indigo, while wastewater and carbon emissions are reduced by over 80% each. This technology has now been extended to the full spectrum of natural pigments, including black and red bio-pigments, and is gradually expanding into applications in food, cosmetics, and pharmaceutical intermediates.

What we want to know

  • 1.Feasibility of in-situ dyeing technology using bacterial-derived bio-based indigo

  • 2.Quantitative impact of fermentation temperature and bacterial strain (BL21) on indigo yield

  • 3.Differences in dyeing effects and stability between bio-based indigo and traditional petroleum-based indigo

  • 4.Practical operational challenges and cost-effectiveness of the repeated dyeing process (9–12 times)

  • 5.Application Directions for Company Products and suggestions for our team.

​​ Renew & Record

In this interview, we further clarified the production and dyeing technical details of bio-based indigo:

  • 1.Indigo extraction and preservation​​: Centrifuge the bacterial broth, remove the supernatant, and dry the bacterial cells to obtain the crude product. In traditional dyeing, the cells autonomously lyse and release indigo in an alkaline environment. Plant-derived indigo paste contains approximately 1% indigo and can achieve good coloring in traditional indigo dyeing. Since the purity of bacterial fermentation-derived indigo is much higher than that of plant-derived indigo, purification is not necessary for dyeing applications.

  • 2.Fermentation process optimization​​: Experts recommended increasing the temperature to 25°C and trying a gradient experiment from 16–25°C; the bacterial strain selected is BL21.

  • 3.Differentiation between bio-based and petroleum-based indigo​​: Bio-based content measurement can distinguish between bio-based and petroleum-based products. In terms of dyeing effects, bio-based indigo appears purple due to the presence of indirubin, while chemical-based indigo is pure blue. Bio-based indigo is more recognized by traditional cultures such as intangible cultural heritage.

  • 4.Dyeing process​​: It is necessary to use sodium dithionite or thiourea dioxide to reduce indigo to water-soluble indigo white, attach it to the clothing, and finally achieve color development through oxidation.

  • 5.Dyeing recommendations​​:

    Use indigo as the base color. Utilize genetically engineered bacteria to produce corresponding pigments, and overlay blue to further develop other new colors. Additionally, when conducting multi-color dyeing, the concentration of indigo must be controlled to achieve a light base.

    If the dyeing effect is unsatisfactory, repeated dyeing can be attempted (traditional plant-derived indigo requires 9–12 cycles to achieve deep blue). Direct dyeing with fermentation broth yields relatively poor results, necessitating exploration of repeated dyeing strategies.

    Regarding the application directions of biosynthetic dyes and team projects:

    • 1.The company has chosen to apply these dyes in traditional Chinese cultural practices such as embroidery and tie-dye, as indigo has always held significant importance in ancient dyeing techniques.

    • 2.There is no need to overly concern ourselves with the general public's bias against biosynthetic dyes. The company has not encountered issues in product promotion due to the use of synthetic biological methods, and public acceptance is gradually increasing.

    • 3.Documenting the growth process of microorganisms is inherently artistic. Team projects could also explore integrating traditional techniques to make the artwork more distinctive.

Dr. Jiang Wei

The Affiliated Central Hospital of Shandong First Medical University

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Dr. Wei Jiang

Light-controlled protein expression

The Affiliated Central Hospital of Shandong First Medical University

He previously published a paper as the first author titled A dual light-controlled co-culture system enables the regulation of population composition. This paper provided significant inspiration for our project design, and we were particularly intrigued by the underlying principle of light-controlled protein expression. Given the technical challenges encountered during our experimental design phase, we sought advice from Dr. Wei Jiang.

Reflect

We contacted Dr. via online email for consultation. He analyzed and responded to the three questions we raised. This online exchange enabled the wet-lab members to deepen their understanding of pathway design and further their knowledge of different protein expression modalities.

What we want to know

  • 1.The sequence length of the blue light-controlled protein YF1 is not a multiple of three. Why is this coding mechanism so unusual?

  • 2.The start codon is designed as GTG instead of ATG. Can the ribosome effectively initiate translation?

  • 3.Could the ATG sequences present in the promoter region lead to misidentification?

​​ Renew & Record

  • 1.Coding Mechanism

    Analysis of the plasmid map reveals that the Open Reading Frame (ORF) of YF1 overlaps with its downstream gene, fixJ. Therefore, it is hypothesized that the complete protein-coding sequence should include the additional 17 nucleotides, taggaggtctagcatga, appended after the originally annotated features. In synthetic biology pathway design, when genes are initiated by the same promoter, overlapping sequences between adjacent genes can occur; however, this would not interfere with protein expression within the pathway.

    Fig. Overlapping Expression

  • 2.Start Codon Selection

    Although ATG is commonly used as the start codon in conventional experiments, alternative start codons may be considered in practical experimental design to balance transcription efficiency driven by different promoters. In this project, GTG serves as the start codon for the YF1 protein, aiming to balance the expression levels of YF1 and FixJ proteins under the control of the same PJ23100 promoter.

  • 3.ATG Sequence within the Promoter Region

    The ATG sequence located in the promoter region is separated from the downstream ribosome binding site by approximately 10 nucleotides and resides in a different reading frame from the downstream ORF. Consequently, it is unlikely to be misrecognized as a functional start codon.

Bioartists

Xiaoyong Zhao

China's Van Goghs

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Xiaoyong Zhao

China's Van Goghs

Zhao Xiaoyong, a featured painter in the documentary China's Van Goghs, spent nearly three decades reproducing Van Gogh's works in Shenzhen's Dafen Oil Painting Village. Over time, he moved from commission-based replication to original creation rooted in everyday observations. With no formal academic training, he honed his technique and color sense through self-learning and long practice. After viewing Van Gogh's originals in Europe in 2018, he shifted firmly to original work, strengthening his belief that anything in life can enter the canvas.

Reflect

We listened to Zhao's interpretation of Van Gogh and Irises, and his insights from nearly 30 years of reproducing Van Gogh's work. We discussed recommendations for recreating Irises in the iRis project using purple, blue, and green pigments, the feasibility of bacterial pigment production, and the priority of biosafety. Our conversation also covered trends in science–art integration, how Dafen's commercial ecosystem shapes artistic pursuit, and the social value of art outreach. Additionally, we considered on-site interpretive guidance for a museum exhibit featuring bacterial Irises, weighed the pros and cons of AI-generated art, and connected the growth variability of E.coli in our project to the artistic notion that imperfection is part of authentic life.

What we want to know

Is our interpretation of Van Gogh and his works well-grounded?

How can we achieve a compelling visual outcome using only purple, blue, and green?

What is the current level of public access to, and openness toward, art?

​​ Renew & Record

  • 1.Understanding Van Gogh and Irises

    Zhao noted that Van Gogh painted many versions of irises, particularly while hospitalized, when the square outside was filled with the flowers. Despite illness and a dimmed outlook, Van Gogh kept hoping for recovery, sustained by his devotion to painting and his yearning for life. Surrounded by irises during each hospital stay, he seemed to regain strength more quickly.

    Among all subjects, irises and sunflowers were likely his favorites—symbols of inner vitality. Some sunflower paintings blaze with brilliance; others pulse with robust life. That intense sense of vitality characterizes much of Van Gogh's work, especially in his depictions of plants.

    In essence, Van Gogh's art is a direct expression of his inner reflections—his understanding and love of life infused into the canvas.

  • 2. Color selection and layering

    We worried that relying only on purple, blue, and green might look thin for Irises. Zhao advised focusing on the dominant palette rather than chasing every detail. The cool triad can map well onto petals, sky, and foliage, preserving the painting's core tonality. While Van Gogh's finer elements (buds, centers) are richer in color, these can be simplified with blue hues and white. Because our bacterial pigments lack the impasto texture of oils and our substrate is flat silk, he recommended practical tests to enhance perceived relief.

  • 3. Why interdisciplinarity matters

    Our project seeks a genuine fusion of science and art. Zhao observed that art schools and studios are increasingly experimenting with mixed media, often achieving striking results. Technology can enable visual effects unreachable by traditional means. Contemporary art naturally evolves by testing new materials and modes of expression. He also cautioned that innovation must be grounded in strong artistic substance—the work should move people on its own, not through buzzwords.

  • 4. Broadening access to art

    Drawing on his years in Dafen, Zhao emphasized how the village lowers barriers to art—through oil-painting experiences and portrait sketching that gently cultivate aesthetic awareness. Compared with decades ago, when viewers walked away if they “didn't get it," more people now pause to consider meaning, showing a rise in public appreciation. For our project, this suggests designing approachable micro-interactions that draw people in first, then deepen understanding.

Zhou Yongjiu

China's Van Goghs

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Yongjiu Zhou

China's Van Goghs

Yongjiu Zhou, one of the protagonists of China's Van Goghs, began his career reproducing oil paintings in Dafen Village. In 1994, an accidental find of Van Gogh reproductions prompted him to practice by copying these works, laying a foundation for his later creation. In 2008, amid the global financial crisis, he shifted to original work and gradually stepped away from dependence on external orders, seeking expressions aligned with his own emotions and thinking. Influenced by nature and everyday life, his art explores the relationship between people and the natural world, and the emotional role of art in daily living.

Beyond his own practice, Zhou volunteers as an art instructor at a charity school, working with autistic and deaf students. His approach—demonstrating first, then encouraging each student's personal expression—explores the therapeutic potential of art. In doing so, he not only imparts technique but also helps students find a voice for their inner worlds, underscoring art's profound impact on people.

Reflect

This interview clarified three key points for us.

First, regarding Van Gogh and Irises: Zhou believes Van Gogh used intense colors to express himself, and that the “white" irises often appear where lighting is strongest. He emphasized Van Gogh's consistent focus on nature and everyday life, which shaped his distinctive emotional language.

Second, on materials and presentation: For recreating Irises on silk with bacterial pigments, he offered practical guidance—mix the three colors; test freeze–thaw or heating to modify texture; and introduce subtle surface relief on silk to mimic the tactile quality of brushwork.

Third, on public engagement: Drawing from Dafen's experience, he noted rising public receptivity to art, though people's paths to understanding differ. Effective exhibitions invite people to pause first, then gradually build comprehension.

What we want to know

With only purple, blue, and green, how can blending and layering best recover the original's dominant hues and depth while keeping experimental complexity manageable?

On flat substrates like silk, which surface treatments most effectively enhance an oil-painting feel?

For general audiences, how can we present microbial art so it is approachable—supported by essential biosafety communication—to reduce unfamiliarity and concern?

​​ Renew & Record

In the next phase, we will refine our workflow and document each experiment and design step in detail.

We will begin with small-scale studies on color ratios and mixing, iterating toward optimal combinations and layering sequences. In parallel, we will compare outcomes under different humidity and temperature treatments to identify conditions that better approximate oil-painting effects. We will also test surface texturing approaches on silk and related substrates to determine methods that balance artistic quality with the distinct characteristics of bacterial media.

For exhibition and engagement, we will develop an intuitive visitor flow that helps audiences quickly understand and experience the fusion of microbial and traditional art without feeling alienated. This includes simple color-based interactions and concise biosafety messaging so people “pause first, then understand," easing acceptance of this new form.

For records and archiving, we will synthesize Zhou's trajectory from copying Van Gogh to establishing his own original practice, as a reference for our project. Each decision and result will be documented, preserving not only experimental outputs but also the evolution of artistic intent and method. These materials will support future interdisciplinary work across science and art.

Ms. Yu Chen

Art teacher

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Ms. Yu Chen

Art teacher

A music teacher in a rural private school

Reflect

Through our conversation with Ms. Chen, a music teacher, we gained insight into the reality of music education in rural private schools: the lack of dedicated music classrooms and instruments, the frequent replacement of music lessons by core academic subjects, and the general neglect from parents. However, students still experience joy in singing activities. This revealed to us that the imbalance in aesthetic education lies not only in material resources but also in the undervaluation of its importance.

What we want to know

We aimed to explore:

1.The main challenges faced by music education in rural schools;

2.Differences in attitudes toward music lessons among parents, teachers, and students;

3.How innovative art forms (e.g., synthetic biology-based art) could help address the lack of aesthetic education.

​​ Renew & Record

Ms. Chen's insights inspired us to:

  • Direct efforts toward under-resourced schools:

    Prioritize rural areas when implementing our synthetic biology art-based education programs.

  • 2.Design contextual teaching

    Combine “bacterial painting” with music lessons in a simple, engaging, and interactive way so students gain a sense of accomplishment from the creative process.

  • Enhance public perception

    Organize exhibitions, workshops, and parent-student sessions to raise awareness about the emotional and creative benefits of aesthetic education.

Dr. Yongze Zhao

Aesthetic Education

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Dr. Yongze Zhao

Aesthetic Education

PhD candidate in Biomedical Science at the University of Macau Applications of machine learning in medical field

Reflect

The interview with Zhao Yongze, a PhD candidate in Biomedical Sciences, highlights multiple challenges in China's aesthetic education:

  • 1.Marginalization of aesthetic education —under exam-oriented systems, music and art remain sidelined, with limited resources and weak institutional support.

  • 2.Lack of aesthetic literacy in society—phenomena such as bizarre architectural designs reflect poor public and administrative taste.

  • Public curiosity and concern toward bio-art—while intrigued by synthetic biology-based art, he expressed concerns over biosafety and ethics.

This suggests that advancing bio-art as a medium for aesthetic education requires not only innovative works but also effective public communication and risk management.

What we want to know

1. Public perceptions and critiques of current aesthetic education in China;

2. Acceptance and ethical concerns surrounding bio-art in the public sphere;

3. How to reduce technical and communicational barriers when introducing synthetic biology-based art into aesthetic education.

​​ Renew & Record

Zhao Yongze offered several actionable recommendations:

  • 1.Simplify scientific communication:

    Avoid excessive jargon, use animations, illustrations, or visual storytelling to explain the “bacterial painting” process.

  • 2.Ensure transparency in ethics and safety:

    Clearly communicate strain sources, waste handling, and biosafety measures in exhibitions and HP activities.

  • 3.Address cost and scalability:

    Develop more affordable and replicable protocols to lower the threshold for art-biology collaborations.

  • 4.Implement aesthetic education strategically:

    Start with exhibitions as a public-facing medium, then expand into workshops, courses, and outreach to create a “high-impact yet low-barrier” aesthetic education model.

Zhuhai Facilitators

A social work organization serving migrant children

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Zhuhai Facilitators

A social work organization serving migrant children

Click here to learn more about Zhuhai Facilitators

Reflect

Through an interview with Zhuhai Facilitators, our partner in conducting courses, we gained insight into the views of a social work organization serving migrant children and the perspectives of their families regarding aesthetic education. We found that the organization places considerable emphasis on aesthetic education, integrating it into their social work initiatives with positive outcomes. They have also expressed strong interest in continuing our collaboration on science and art integrated courses.

What we want to know

1. Can microbial art in the team's curriculum help dispel negative perceptions of microorganisms to some extent?

2. The forms of aesthetic education activities currently offered by the organization and the children's gains;

3. The gap between parents' and children's understanding of aesthetic education;

4. The underlying value of aesthetic education and the level of societal emphasis on it;

5. The feasibility of in-depth collaboration between the organization and the team on science and art projects.

​​ Renew & Record

  • 1. For children , their natural curiosity toward novel things makes them more receptive than adults who may have cognitive barriers. The integration of artistic forms in the curriculum transforms abstract knowledge into hands-on practice, which primarily enhances memory and engagement.

    Visualizing bacteria through art helps break the stereotype that “all bacteria are dangerous," conveying a more scientific perspective of “coexistence between microbes and humans." This approach offers a fresh cognitive angle and can help alleviate fear.

  • 2. Aesthetic education holds significant importance at Zhuhai Facilitators

    • •Environment Building:

      Natural aesthetic spaces are created through wooden decorations, wall paintings, and handmade signs, countering the often messy and disordered living conditions of migrant children. This conveys the idea that “beauty is co-created" and encourages participation in community building.

    • •Activity Design:

      Handmade poster creation: Mixed-age collaboration (coloring/drawing/idea generation) stimulates self-expression and teamwork; Non-templated teaching: Rejects standardized outputs (e.g., providing only a circular outline for drawing a face) and encourages personalized expression;

      Museum visits: Expand aesthetic experiences (ancient architecture/historical artifacts) and plant seeds for cultural enlightenment.

  • 3. Parents' attitudes toward aesthetic education are :

    • •Utilitarian view: Families facing hardships prioritize academic performance and see aesthetic education as a “distraction from studies";

    • •Supportive view​​: Some parents are willing to invest in their children's interests and recognize the value of holistic development.

    • •Children demonstrate strong demand:

      They show great enthusiasm for art courses and clear willingness to continue learning after class. However, many such courses are fee-based and thus financially inaccessible.

  • 4. Social workers interviewed generally acknowledge the value of aesthetic education—including its role in healing and essential literacy development—and recognize its positive psychological impact on children.

  • 5. The organization strongly agrees with collaborating on science and art integrated courses. They believe sustainable cooperation can take multiple forms, such as bringing programs into schools and training children to become young instructors.

Research on Public Art Perception and Aesthetic Education Biases

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Research on Public Art Perception and Aesthetic Education Biases

Overview:

This survey aims to gain insights into the Chinese public's awareness of art and the practical challenges of aesthetic education. The findings reveal that while the public highly recognizes the value of art and the importance of aesthetic education in principle, in reality, aesthetic education has been marginalized due to "utilitarian social values", "exclusion from standardized testing" and "uneven resource distribution" resulting in passive and superficial art participation. This highlights the core contradiction in promoting aesthetic education and underscores the necessity and foresight of our project, which employs low-threshold, highly participatory bio-art innovation to break the deadlock and restore aesthetic education to its essence of perception and creativity.

By September 30,2025, we had collected a total of 217 questionnaires in China, with the age distribution as follows.Overall, our survey population was dominated by young people aged 18-30. As the most active and influential segment in society, this group has artistic aesthetic orientations and acceptance levels that largely indicate the future direction of public aesthetic education, most accurately reflecting the current societal acceptance of innovative art forms and existing cognitive biases.

Figure 1: Age distribution of respondents (The answer to "age")

The distribution of social identities among our survey respondents is as follows: Overall, the majority of respondents were students, followed by teachers, with a small proportion being working professionals and other employed individuals. Among the teacher group, most taught academic subjects such as Chinese, English, chemistry, and biology, with only a few involved in art-related courses. Within the working professionals group, there were specialists in fields like biotechnology, art restoration, and art therapy, as well as practitioners from numerous other industries—ranging from cutting-edge technological innovation sectors like information technology to foundational service areas like healthcare, and even industries bridging technology and personal consumption, such as the beauty industry. This diversity ensures the comprehensiveness of the survey results.

Figure 2: Social identities of respondents (The answer to "identity")

Figure 3: Teaching disciplines of the faculty group (The answer to "subjects taught")

Figure 4: Career directions of Professionals (The answer to "Career Orientation")

After characterizing the demographic profiles of our survey respondents, we further analyzed their perspectives on art-related issues. Below are the definitions of art provided by the participants. Overall, painting and music received the highest recognition, reaching approximately 95%, followed by film, theater, sculpture, and dance, with recognition rates hovering around 88.5%. Lastly, cooking and gaming garnered recognition rates of about 69% and 64%, respectively. Additionally, some respondents supplemented their personal definitions of art, such as "any concept or entity that satisfies aesthetic needs", "things that originate from life yet transcend it—beauty defined differently by each Homo sapiens", and so on. This indicates that traditional aesthetic education has successfully popularized classical art, yet struggles to respond to the diversity of contemporary art. Therefore, establishing an inclusive aesthetic framework has become an urgent necessity, which also points the way for our project to promote innovation in aesthetic education.

Figure 5: Respondents' definition of art (The answer to "art definition judgment responses")

We subsequently investigated the frequency and forms of art participation among respondents, with the following findings. Overall, 34% of participants engage in art multiple times weekly or occasionally, followed by 23.5% who participate monthly, while those who rarely engage account for the smallest proportion. Regarding engagement formats, online art appreciation and offline exhibition/performing arts visits dominate, with participation rates reaching 78.8% and 66.36% respectively. Meanwhile, self-creation and art course participation rates remain below 50%. This indicates that current public engagement in art remains passive and superficial. Art education and aesthetic cultivation efforts should not merely provide richer artistic content for public consumption, but must transform the public from "spectators" to active "co-creators." This insight suggests that our project applications should adopt universal applicability and low barriers to entry, enabling broader public participation in artistic creation processes.

Figure 6: Frequency of artistic participation among respondents (The answer to "frequency of personal artistic participation")

Figure 7: Forms of artistic participation of respondents (The answer to "Forms of personal artistic participation")

We then analyzed the respondents’ views on art and aesthetic education, with specific results as follows. Respondents generally agreed that "aesthetic education can enhance people's life happiness", but were neutral or slightly opposed to the view that "community art museums are as important as hospitals". The statements "art education has limited help for scientific employment" and "school art classes are secondary to core subjects like mathematics and Chinese" received neutral or slightly supportive ratings. This indicates that the Chinese public has highly recognized the intrinsic value and personal significance of art ideologically, but demonstrates a highly cautious and pragmatic attitude when addressing practical issues such as resource allocation, utilitarian utility, and institutional integration. This also highlights the core challenge in promoting aesthetic education today: designing practical solutions that bridge spiritual artistic pursuits with real-world concerns, rather than merely discussing its importance.

Figure 8: Average agreement of respondents on views related to art (The answer to "Please choose the most appropriate item according to your actual situation: 1→5 indicates strong disapproval→strong approval")

To investigate the current state of aesthetic education marginalization, we surveyed respondents regarding their perceptions and observed phenomena related to this issue along with underlying causes.

Figure 9 illustrates the prevalence of marginalization-related phenomena. Approximately 3% of respondents answered "none" in the "other" category. Some mentioned specific instances such as the absence of art courses starting from high school, schools conducting art classes merely as formalities rather than fulfilling aesthetic education objectives, and universities treating artistic literacy as a comprehensive evaluation tool.

Figure 10 illustrates respondents’ agreement with the notion of "aesthetic education being marginalized", with specific results as follows: 76.98% of respondents endorsed this view. Regarding those who opposed it, our analysis of their arguments revealed differing interpretations of the question. Some respondents maintained that aesthetic education is crucial and should not be marginalized. Others noted that aesthetic education has gradually gained societal recognition, while some argued that "the scope of marginalization needs clarification and the current situation should be acknowledged within the exam-oriented education framework". Conversely, others expressed reservations, stating it might simply be "artists' self-perceived biases".

Figure 11 highlights primary causes of aesthetic education marginalization, with 85% attributing it to "social utilitarian values", establishing the macro-social context of this challenge. The institutional causes of aesthetic education marginalization are twofold: "The college entrance system does not assess art" and uneven distribution of educational resources. The 59.28% recognition rate of "parental cognitive biases" reflects utilitarian values at the family level. These findings clearly expose systemic challenges in implementing aesthetic education. Data consistently highlight a core contradiction: while the ideal value of aesthetic education enjoys widespread acceptance, its implementation within the current education framework often suffers from marginalization, utilitarian tendencies, and superficial formalism.

Figure 9: The existence of marginalization of aesthetic education (The answer to "Do you observe the following phenomenon in your life?")

Figure 10: Respondents’ agreement with the view that "aesthetic education is marginalized" (the answer to the question "Do you agree that aesthetic education is marginalized (which can be simply understood as aesthetic education is not valued)")

Figure 11: Main reasons respondents think aesthetic education is marginalized (The answer to "What do you think are the main reasons for aesthetic education being marginalized?")

To most intuitively probe the public's genuine social attitudes and underlying biases toward art education, we designed a scenario question about "first reactions when seeing neighbors' children learning painting or musical instruments". The majority of respondents endorsed "nurturing interests is beneficial", while a minority expressed concerns that neighbors might "intend to enroll in art-specialized programs" or "worry about academic performance". Only a small percentage considered it "a wasteful and useless investment". In the "other" category, respondents shared perspectives like "forced by parents", "I'd love to learn if I could", and "hope the children genuinely enjoy art rather than parents demanding hobbies". These findings reveal a paradoxical social mentality --- where widespread conceptual support coexists with practical utilitarian anxieties. The overall societal endorsement reflects multiple layers of criticism regarding educational alienation, aspirations for artistic purity, and personal sentiments.

Figure 12: Respondents 'first reaction when they saw their neighbor's child learning to draw or play an instrument (The answer to "When you see your child learning to draw/instrument, what's your first reaction?")

Our research exposes the persistent challenge in aesthetic education: while its value gain recognition, they remain marginalized. This is precisely why our project carries profound significance. By employing low-cost biological kits to challenge resource inequality, we spark creativity through life's natural inspiration rather than forced indoctrination, allowing aesthetic education to reconnect with genuine appreciation and passion. This endeavor transcends mere science—it can stand as a groundbreaking social experiment shaping the future of aesthetic education.

Dr. An Liu

Public Engagement

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Dr. An Liu

Public Engagement

School of Future Design, Beijing Normal University

Research Interests

  • 1. Slow fashion and sustainable fashion

  • 2. The intersection of fashion and positive psychology

  • 3. Contemporary expression and reinvention of traditional culture

Reflect

Through our discussion with Teacher Liu, we realized that safety and psychological acceptance are crucial when involving the public in art practices. Even if microbial art offers unique creativity and aesthetics, requiring participants to directly engage with “live bacteria” may raise safety concerns or mental discomfort, thereby reducing participation. Public engagement is not only about technical demonstration but also about creating a safe, acceptable, and meaningful experience. Teacher Liu’s marbling workshop experience reminded us that interdisciplinary art practices must balance technical controllability with public perception to achieve genuine participation and recognition.

What we want to know

We aimed to explore:

1.The feasibility and potential challenges of introducing microbial art into public engagement activities;

2.How to balance safety and user experience when designing participatory processes;

3.Approaches to help the public move from “uncertainty and resistance” to “understanding and acceptance.”

​​ Renew & Record

Teacher Liu’s advice provided valuable guidance for us:

  • 1.Shaping public sense of safety:Beyond biosafety measures, it is equally important to consider participants’ psychological comfort and minimize unease about “live bacteria.”

  • 2.Necessity and meaning:The uniqueness of microbial art should be explained through “why this method,” helping the public see its artistic and inspirational significance rather than perceiving it as a gimmick.

  • 3.Interactive design optimization:Inspired by the marbling workshop, we could guide participants from simple pattern creation to applied works in stages, enhancing both control and accomplishment.

  • 4.Balancing global and local perspectives:Teacher Liu noted that international exhibitions emphasize safety protocols, while domestic audiences focus more on visual effects—reminding us to balance both expectations in our project design.

Survey for Public's Acceptance of Microbial art

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Survey for Public's Acceptance of Microbial Art

Overview

This survey aims to understand the public's acceptance of microbial art and explore more possibilities for the team project. The results show that the respondents have a relatively high level of knowledge about microorganisms and are able to accept this form of art, but there are concerns regarding safety and ethics.

Figure 1: Age distribution of respondents

Figure 2: Social identities of respondents

Overall, our survey population primarily consists of young adults, who, as the most influential demographic in society, represent a key indicator of future trends in public scientific literacy and artistic appreciation. This group is also the primary target audience for emerging forms of artistic expression. Additionally, the survey includes a certain proportion of middle-aged participants. In terms of professional distribution, the respondents are predominantly students, followed by educators, with a smaller number of individuals from other occupational backgrounds.

Subsequently, we investigated participants' fundamental understanding of microorganisms. Overall, the level of awareness demonstrated was relatively high, with some nuanced variations observed.

Figure3: Perceived role of microorganisms

Figure4:​Known microbial applications

Figure5:Attitudes toward genetically modified microorganisms

  • 1.Regarding daily functions, the majority of participants perceived microorganisms as having ​​mixed impacts (both beneficial and detrimental)​​, while demonstrating awareness of common application scenarios such as yogurt production and wastewater treatment.

  • 2.For genetically modified microorganisms, ​over 80% of participants maintained a supportive stance toward their development but emphasized stringent oversight​, particularly for risk mitigation (e.g., safety failures and ethical concerns); only a small minority expressed complete opposition or indifference.

Building upon this foundation, we investigated the participants' familiarity with microbial art and found that awareness was generally limited: the majority had only heard the concept (32.67%) or seen images (43.08%), while a significant proportion had never encountered the term (23.27%). This highlights the pioneering nature of our project domestically and underscores the necessity for awareness-raising efforts. Encouragingly, however, many respondents exhibited curiosity and anticipation when introduced to the idea of "using bacteria to create artwork," demonstrating openness to its artistic value.The acceptance scale demonstrates a ​​significantly high mean score.Notably, concerns regarding safety were frequently raised, reminding us to prioritize safety considerations in project promotion—a aspect for which we have corresponding preparations in place.

Figure6:Prior exposure to microbial art

Figure7:Initial reaction to bacterial artwork creation

Figure8:Acceptance Level

While our research received ​​positive reception regarding acceptance levels​​, over half of the respondents expressed ​​concerns about microbial art​​, primarily focused on ​ ​ethical and safety issues ​​, with ethical review receiving significant attention. Some respondents also expressed apprehensions regarding ​​artistic merit and visual outcomes​​. Based on these findings, our team continues to refine its approach and has sought recommendations and direction through interviews.

Figure9&10:Concerns about microbial art

Figure11:​Need for ethical review

To explore how the presentation of project outcomes could be more engaging, we investigated participants' perceptions of the appeal of microbial art. All options provided in the questionnaire received recognition​, a finding that has directed our DRY LAB work.

Figure12:Core appeal recognition

​​Regarding preferred promotional formats, the results are as follows: physical interactive experiences led by science museums/museums emerged as the most favored approach, while alternative formats also demonstrated notable traction.​ Among the mentioned promotional formats, DIY bio-art kits have the largest acceptability (61.39%), though not the preference of most people, followed by social media short videos (50.5%), and finally artist-scientist dialogues and documentaries (both at 30.2%). This suggests that in promotional applications, we could design relevant offline experiential kit packages. Additionally, we have explored more promotional approaches, such as the Microbial Melody handled by the modeling team.

Figure13:Preferred experience venues

Figure14:Preferred promotional formats

Bioartists

Dr. Yihao Li

Art Healing

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Dr. Yihao Li

Art Healing

Postdoctoral Researcher at the Center for Biotechnology Research, Academy of Natural Sciences, Beijing Normal University at Zhuhai. His research focuses on the dynamic regulation and function of the cytoskeleton in plant immunity, as well as the development of novel research methodologies.As the faculty advisor of the Biology Club at the Zhuhai Campus, he has . He offers a unique perspective at the intersection of biology and art healing.

Biotechnology Research

Receives training in art healing

Possesses extensive workshop experience

Reflect

Through this art healing workshop, we gained substantial insights. The instructor introduced us to the concepts and methods of art healing, explaining how specific forms such as painting, poetry, drama, paper tearing, and collage can be used to express and alleviate emotions. We deepened our understanding of the difference between art healing and ordinary artistic creation—it focuses more on connecting with one's inner self and expressing genuine feelings. Participants shared their experiences with art healing and explored innovative applications such as "bacterial painting." The workshop also outlined the potential for art healing to be applied in hospitals and schools, encouraging everyone to actively practice and promote this field.

What we want to know

1.Hands-on Experience in an art healing Workshop

2.Understanding art healing from a Biology Professional's Perspective

3.Exploring Potential Applications of the Project in art healing

​​ Renew & Record

  • 1. Core Consensus on art healing

    The essence of art healing lies in connecting with one's inner self, expressing and transforming emotions through the creative process—such as painting, drama, and handcrafting—rather than pursuing artistic quality in the final work. Unlike traditional artistic creation, art healing places greater emphasis on subconscious expression and emotional release.

  • 2. Unique Therapeutic Value of "Bacterial Growth" Creation:

    The process of "waiting for bacterial growth" cultivates participants" patience and concentration, while enhancing their perception of natural rhythms through collaboration with living organisms.

    This approach emphasizes the process over the outcome, aligning with art healing's focus on experiential engagement and inner connection.

  • 3.Suitable Groups and Contexts

    It is well-suited for individuals seeking emotional guidance, stress management, or creative expression—particularly effective in small group settings (6–7 people). Guidance methods should be adapted to participants' backgrounds; for example, simplified instructions and a sense of safety should be provided for children or anxious groups.

  • 4.Technical Packaging and Workshop Implementation Intentions

    If the technology can be packaged in a safe and user-friendly form (e.g., a toolkit), small-scale workshops could be conducted in the future to explore the combined effects of bacterial growth and art healing.

    If the technology can be packaged in a safe and user-friendly form (e.g., a toolkit), small-scale workshops could be conducted in the future to explore the combined effects of bacterial growth and art healing.

How we take responsibility&response:

  • 1.We will promote art healing courses and activity plans in collaboration with partner institutions such as the Xinkang Center.

  • 2.We will focus on innovative applications of nature and life themes in art healing and track practical feedback in clinical and educational settings.

Prof. Yi Tang

Art Therapy

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Prof. Yi Tang

Art Therapy

School of Arts & Communication, Beijing Normal University

Research Interest:

  • 1. Inheritance and innovation of Chinese ethnic and folk dance

  • 2. Art therapy and neuroaesthetics based on bodily movement

  • 3. Body language analysis and emotion decoding in dance

Reflect

Our interview with Ms. Tang offered profound insights into both the potential and the limitations of dance therapy in mental health. On the expressive level, bodily movement enables emotional release beyond language, bypassing cognitive defenses and reviving emotions frozen by trauma—particularly valuable for children, individuals on the autism spectrum, and those with alexithymia. On the functional level, art emerges not only as a tool for healing but also as an “early sensor” for psychological risks, playing a foundational role in everyday emotional regulation and resilience building. Yet, its dissemination faces structural barriers: a severe shortage of school psychologists makes it difficult to implement art-based interventions, especially in rural settings. This underscores the need for cross-disciplinary collaboration, teacher training, and integration of social initiatives to make such resources accessible. The conversation also reframed how we see the role of our microbe-art project: beyond aesthetics, it can become a medium of psychological support and a catalyst for social innovation.

What we want to know

1.How does dance therapy facilitate trauma release through body–emotion linkage?

2.What mechanisms enable art to serve as prevention and screening tools?

3.How can art therapy be scaled where psychological staff is insufficient?

4.What additional skills are needed when integrating a light-controlled microbial feedback system?

​​ Renew & Record

Ms. Tang offered actionable recommendations for our project:

  • 1.Define the human–media–emotion interface:link body movements to microbial light/color/sound feedback with symbolic meaning, ensuring the system supports rather than controls expression.

  • 2. Enable group co-creation: use the system as a collaborative medium to enhance resonance and group bonding.

  • 3.Prioritize ethics and safety: ensure informed consent, adjustable stimuli, and trauma-sensitive guidance.

  • 4.Develop cross-disciplinary training:include biofeedback basics, scenario simulations, group workshops, and ethical guidelines.

  • 5. Promote “psychology + art” integration: leverage teacher training and social partnerships for scalable implementation.

Tiange Zhou

Microbial Melody

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Zhou Tiange

Microbial Melody

School of Future Design, Beijing Normal University at Zhuhai

Specially-Appointed Associate Researcher

Research Areas: Composition, Computer Music, Sound Design, Audiovisual Interaction, Performing Arts, Cross-Media and Interdisciplinary Collaboration & Creative Research.

Reflect

After communicating with Professor Zhou, we identified the core shortcomings of our previous visual-to-auditory conversion approach and defined a new direction for audiovisual material selection. We also gained a clearer understanding of the limitations of the original conversion method and received recommendations for specialized software tools. Under Professor Zhou’s guidance, we developed a deeper awareness of the innovation and content adaptability required in audiovisual conversion. It became clear that whether based on the original painting themes or the newly chosen microbial subject matter, the converted music must form a coherent composition rather than fragmented notes. Following this discussion, we updated the core data of the audiovisual module to reflect the growth process of E.coli, establishing a more biologically relevant and innovative foundation for subsequent development. This progress has significantly strengthened the team’s confidence in refining the conversion strategy.

What we want to know

1. Evaluate our previous visual-to-auditory correspondence relationships and conversion methods.

2. To see if there are more reasonable conversion approaches.

​​ Renew & Record

  • 1.Regarding Materials for Audiovisual Conversion

    We initially intended to convert visual artwork into music. However, Professor Zhou pointed out that many existing projects have already established connections between image colors and music, making our approach less innovative. Instead, he suggested focusing on microbial growth processes, which are more dynamic and closely aligned with the concept of "biology." Accordingly, in our updated audiovisual conversion module, we have chosen to use growth data of E. coli to generate music.

  • 2.Our Previous Audiovisual Conversion Method

    Professor Zhou advised against continuing with our original conversion method, which involved using the K-means clustering algorithm to extract dominant colors from paintings and then converting their RGB values into corresponding musical notes. He emphasized that this approach significantly overlooks the color gradient characteristics of Post-Impressionist art—forcing inherently continuous decimal values into disjointed integers fails to capture the essence of the artwork. Similarly, even with the new microbial theme, the conversion should produce coherent music rather than fragmented notes

  • 3.Recommended Software and Tools

    Professor Zhou recommended using tools such as Max, developed by Cycling '74, for the conversion process.

How we take responsibility&response

  • 1.Shift the focus of musical material selection to microorganisms.

  • 2.Utilize the software recommended by the instructor for subsequent music production.

Bioartists

Zhuhai Facilitators Field Research

A social work organization serving migrant children

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Zhuhai Facilitators Field Research

A social work organization serving migrant children

Click here to learn more about Zhuhai Facilitators

On June 28,2025, we conducted first on-site research at the Zhuhai facilitators Base. This visit provided us with insights into Zhuhai facilitators’ history, its conditions, and migrant children's situation. We also engaged in discussions with collaborators regarding our designed curriculum outline, making targeted adjustments based on their feedback.

The following detailed suggestions and improvements were proposed:

  • 1.Incorporate interactive games during peer recognition sessions to foster relationships.

  • 2.Establish group agreements with each team to jointly formulate classroom rules.

  • 3.Enhance cooperation awareness through group points system while motivating initiative by appointing group leaders.

  • 4.Streamline course content from six activities to four: retaining "Microscopic Cell Observation", "Petri Dish Graffiti Experiment", "DIY DNA Necklace", and "Cell Planet Construction". Following teachers 'recommendations, the "Cell Planet Construction" activity was transformed from paper cutting to clay modeling.

In the end, Teachers specifically reminded us to obtain consent before using children's photos, leading to prior agreement signing before class commencement.

Zhuhai Facilitators

A social work organization serving migrant children

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Zhuhai Facilitators

A social work organization serving migrant children

Click here to learn more about Zhuhai Facilitators

Reflect

Through this interview, we have gained a deeper understanding of the challenges faced by migrant children, particularly in terms of educational resources, family environment, and living conditions, as well as their lack of access to science educational resources. At the same time, we have learned about the current state of social work, including both the improvements made in the children’s situations and the ongoing difficulties. This process has enhanced our awareness of the conditions of the local migrant children population and provided direction for refining our curriculum.

What we want to know

1.Policy Restrictions and Core Dilemmas for Migrant Children

2.Educational Pathways and Tracking Status of Migrant Children in Zhuhai

3.Goals of Facilitators Activities and Children’s Gains

4.Parental Awareness of Educational Policies and Information Barriers

5.Motivation and Challenges in Social Work

6.Demand for Curriculum Resources and Directions for Improvement

Renew & Record

1.Migrant children face dual pressures of economic hardship and academic challenges:

  • Families commonly experience financial strain (low wages, informal employment, lack of social security).

  • Limited access to educational resources; most cannot enter public high schools (due to household registration or point-based requirements).

  • Main causes of household registration barriers:​​

    Requirements for permanent residency include educational background, stable employment, social security contributions, and property ownership—conditions difficult for struggling families to meet.

    Public schools prioritize local students, leaving few spots for migrant children (e.g., only one spot available in a certain year).

2.Migrant children exhibit relatively low rates of progression to higher education. Many end up with limited options, often engaging in manual labor.

3.Logic behind Facilitators’ activities:​​

  • Address resource gaps (e.g., self-awareness, social skills, platforms for parent-child interaction).

  • Tackle isolation among children (promote community engagement, reduce smartphone dependency).

  • Actual outcomes:​​

    Initial difficulties in mobilization, but participants gradually opened up and showed increased willingness to communicate.

    Summer programs provided safe learning environments, offering an alternative to unsupervised home settings.

4.Access to educational policy information is highly unequal:​​

  • Parents of children in public schools receive policy guidance, while those in private schools are often kept in the dark (schools may withhold information to retain students).

  • Migrant families generally lack proactive channels to obtain policy-related information.

  • Organizations attempt to connect with external resources (e.g., online course enrollment guidance), but localized support remains insufficient.

5.Social work is a long-term endeavor that requires sustained effort to yield results. Challenges include uncooperative parents and resource wastage. However, long-term follow-up shows visible positive changes in children.

6.Popular science resources in Zhuhai’s western district are significantly fewer than in Guangzhou and Shenzhen. Science courses are in high demand but lack specialized academic support.

Courses should inspire children’s intrinsic motivation to explore and encourage active participation.

Yuxian Ye, PingLin

Special Education

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Yuxian Ye, Ping Lin

Special Education

  • 1.Ms. Yuxian Ye:

    With 5 years of experience in special education, she has participated in Yimixing's Flexible DTT Online Course, MY Star Online Teaching Training, PCI Social Game Core Theory Course, and training on providing effective group courses for developmental children. She attends the annual Special Training Workshop on Knowledge and Skills for Childhood Autism organized by Zhuhai Maternal and Child Health Hospital, as well as the Professional Technical Training on Rehabilitation for Children with Developmental Disabilities held by the Guangdong Provincial Association of Rehabilitation for Persons with Disabilities. She holds a certification in autism rehabilitation education and specializes in individualized teaching, social group teaching, group course instruction, integration management in mainstream schools, speech-language therapy, and sensory integration rehabilitation training.

  • 2.Ms. Ping Lin:

    With 5 years of experience in special education, she has attended multiple training programs, including the Special Training Workshop on Knowledge and Skills for Childhood Autism by Zhuhai Maternal and Child Health Hospital, the Professional Technical Training on Rehabilitation for Children with Developmental Disabilities by the Guangdong Provincial Association of Rehabilitation for Persons with Disabilities, the Provincial Standardized Training Workshop for Speech Rehabilitation Technicians and the Practical Operational Techniques Training for Speech Rehabilitation of Special Children, as well as standardized training on the (S-S Method) for assessing language development delays in children, and practical tutoring workshops on individual oral motor/speech assessment and training. She is proficient in assessment tools such as PEP-3, VB-MAPP, and ABLLS-R, and excels in using ABA for one-on-one teaching and customized social group courses. She provides professional assessments and develops individualized teaching plans for young children to enhance their cognitive understanding, social skills, language expression, and other abilities, helping them fully realize their potential.

Reflect

Through interviews with the two teachers, we gained insights into the current state of education for children with neurodevelopmental disorders in Zhuhai, including the curriculum offerings and how the children are adapting. Additionally, we asked the teachers for feedback on the preliminary instructional design and received guidance such as the need for simple and clear instructions, and the use of physical models where possible. These suggestions have been incorporated into our curriculum.

What we want to know

1.Lack of Science Popularization Resources

2.Educational Status of Special Needs Children in Regular Schools and Special Education Schools

3.Directions for Improving Existing Curriculum Design

Renew&record

  • 1.The most critically lacking and urgently needed resource: professional teachers.

    Teachers must understand the individual differences and language comprehension characteristics of children with autism to effectively guide their participation. Courses should incorporate more collaborative interactive content to promote communication between children and their peers as well as adults.

  • 2.Current state of special education curriculum:

    The interviewed teachers had limited knowledge about the specific curriculum in special education schools. Information gathered from parents indicates that these schools primarily offer practical subjects such as Practical Mathematics, Practical Language, and Life Adaptation. It remains unclear whether science-related courses are included.

    Learning in regular classrooms and inclusive education:​​

    Placement in regular classrooms is typically initiated by parents. Currently, most public schools in Xiangzhou District allow shadow teachers to accompany students in regular classes. However, school cooperation remains less than ideal, and some general education teachers still believe that special needs children should receive education in special education schools.

    The key to achieving high-quality inclusive education lies in effective collaboration between general education teachers and special education support systems. Nevertheless, the current integration mechanisms still require further refinement.

  • 3.Suggestions for improving instructional activity design:

    Provide physical objects or models to enhance visual clarity. Use more images and short videos while reducing text-heavy content. Allocate more time for drawing and hands-on activities, as special needs children generally show strong interest in operational tasks.

    Suggestions for creating a comfortable communication environment:

    Instructions should be concise and clear; prioritize visual cues over verbal explanations.

    Implement tiered instruction by setting different goals based on children’s abilities.

    Children with weaker expressive skills can communicate through methods like imitative speaking (echolalia), with teachers providing timely assistance.

What we will do

While we have accomplished many of our initial goals, there remain areas with great potential for further exploration and refinement. Looking ahead, we have outlined several directions to continue improving and expanding our project. The following plans represent how we aim to build upon our current work and bring it to a more comprehensive level in the future.

Lack of conversation

1.The government

At the very first of this aspect, we plan to initiate dialogue with relevant local and national departments in China, such as the Zhuhai Environmental Protection and ecology Association and the National Center for Biotechnology Development. Our goal is to:

  • Present a comprehensive biosafety dossier detailing the containment measures and environmental risk assessment of our engineered strains.

  • Explore pathways for policy advocacy, contributing to the development of clear regulatory frameworks for bio-art materials and their commercial application.

  • eek guidance on scaling our technology from the laboratory to controlled industrial or community settings.

2.Industry Partners

To translate our proof-of-concept into tangible products, we will proactively reach out to potential industry partners.

  • Textile and Fashion Companies: Collaborate with sustainable brands to test our microbial dyes on a pilot scale, assessing durability, cost-effectiveness, and consumer acceptance.

  • Medical and Therapeutic Institutions: Establish partnerships with hospitals and rehabilitation centers to design and conduct clinical trials for our art therapy protocols, ensuring they meet ethical and efficacy standards.

Furture application

1.Art Therapy & Art Healing

We planed to collaborate with the related professionals after our work have done completely. Before that, we learnt about some significant information and considerations through interviewing.(It is possibly accessible for us to complete in the following ways):

  • Co-develop standardized therapeutic toolkits with certified art therapists and psychologists. These kits will include tailored protocols for using our light-controlled dyes with specific populations.

  • Train practitioners on the safe and effective use of our bio-art tools in therapeutic settings.

2.Sustainable Fashion
  • Community Workshops: Establish a social enterprise model where community members can learn the skills to produce and use these dyes, fostering local economic development centered on sustainability.

  • Creative application in sustainable fashion fields: Encourage collaboration between local artisans and sustainable fashion designers to create unique, eco-friendly clothing lines.

3.Bacterial Art Legal and Ethical Framework

Pioneering Regulatory Guidelines: Propose a collaborative framework with legal experts, bioethicists, and microbiologists to address novel legal considerations in bacterial art, including biocontainment standards for public exhibitions, and liability protocols for unintended ecological impact.

Concluding words

As an emerging medium, bioart is calling for society to re-examine how life sciences and art can collaboratively create a future—where beauty and knowledge are truly shared by all. Our iRis project embodies this vision through light-controlled bacterial programming that enables dynamic artistic creation, demonstrating a new paradigm of science-art integration.

However, realizing this vision cannot rely on a single force. It must evolve into a systematic framework: breaking down disciplinary barriers through interdisciplinary and cross-cultural Collaboration, laying sustainable foundations by empowering education for the next generation of bio-art creators, and ensuring inclusivity to make this bio-art revolution truly benefit everyone.

Guided by clear implementation strategies, we are committed to transforming this vision into tangible, sustainable real-world impact. We believe that when science, art and humanistic care converge here, they can collectively paint a more creative, inclusive, and vibrant future. Finally, we cordially invite you to join this journey—of collaboration, education, and inclusion, co-imagining a world where life itself is art and gradually turning it into reality.

"Normality is a paved road,it's comfortable to walk,but no flowers grow on it."

——Vincent van Gogh