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Ginseng, known as the “King of Herbs”, is a precious medicinal plant and is widely used in clinical practice.

Rare ginsenoside Rh1 is one of the terpenoids with significant pharmacological activity in ginseng.

In recent years, ginseng cosmetics have gradually entered the market and the scale has been continuously expanding. Rh1 can significantly promote the synthesis of collagen in skin fibroblast cells, effectively improving skin wrinkles and is applied in skin care products.

However, the traditional methods for obtaining Rh1 mainly involve plant extraction and chemical synthesis.

But the output is very low, resulting in the high price of Rh1 and cosmetics. It also damaged the environment at the same time.

We dive into the sea and find new raw materials.

In addition, galactose from red algae hydrolysis is an advantageous carbon source for terpenoid production in Saccharomyces cerevisiae, an optimal chassis cell with MVA pathways , as it avoids the Crabtree effect.