HERO animation

The Age of Tiny Giants In the 21st century, bacteria are no longer just seen as enemies; they are becoming our allies. We've learned how to study them, how to engineer them, and how to recognize both their superpowers and their weaknesses.

Intro image 1

Earth's Silent Healers In the critical field of remediation - cleaning our Earth from pollutants - we have found many bacteria that can help us slow down environmental change and offer truly sustainable solutions.

Intro image 2

Sailing into the Future It's time to move beyond traditional physical and chemical remediation methods and embrace safe, tailored biological strategies.

Intro image 3

The Problem Many promising microbes are difficult to study because they grow poorly in labs and lack genetic tools, limiting their potential for safe and innovative biological solutions.

Our Solution With a Cre recombinase-loxP system in its genome, a set of promoters, a metabolic pathway prediction tool, and a lipid biosensor, we aim to transform Rhodococcus opacus PD630 into a safe, adaptable, and customizable platform.

Intro image 4

Why? We chose Rhodococcus opacus PD630 for its robust metabolism, genetic accessibility, and extraordinary lipid accumulation, reaching
1%
of dry cell weight under gluconate-grown conditions.

From ideas to HERO Follow the journey toward creating our bioremediation chassis.

Comic panel 1 Comic panel 2 Comic panel 3

HERO

High-performance Engineered Rhodococcus Opacus

Front left cape
Front right cape

CAPE
A software that predicts new metabolic pathways in HERO

HERO
A R. opacus PD630 powered by an integrated Cre/loxP recombinase system.

HELMET
A biosensor capable of quantifying the most interesting HERO products: triacylglycerols.

Special cards from our board game can be found in some of our wiki pages. Try to find them all to discover the key components of our project and to explore our work in more detail!